First case of resistance to tigecycline by Klebsiella pneumoniae in a European University Hospital

Neonakis, I. K.; Stylianou, K.; Daphnis, E.; Maraki, S.
January 2011
Indian Journal of Medical Microbiology;Jan2011, Vol. 29 Issue 1, p78
Academic Journal
Case Study
The article presents a case study of a 62-years old female with an end-stage renal disease secondary to adult dominant polycystic kidney disease, who was recurrently admitted due to cholangitis. Her prior medical history included chronic hypertension, hysterectomy, and bilateral nephrectomy. It mentions a variety of Gram-negative and Gram-positive microbia that have been isolated and tigecycline (TIG) was extensively used. It notes TIG-resistance attributed to overexpression of efflux pumps.


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