TITLE

A clinical comparison of etomidate-lipuro, propofol and admixture at induction

AUTHOR(S)
Saricaoglu, Fatma; Uzun, Sennur; Arun, Oguzhan; Arun, Funda; Aypar, Ulku
PUB. DATE
January 2011
SOURCE
Saudi Journal of Anaesthesia;Jan2011, Vol. 5 Issue 1, p62
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Objective: The purpose of this study was to compare etomidate-lipuro and propofol and 50%, (1:1) admixture of these agents at induction with special reference to injection pain, hemodynamic changes, and myoclonus. Methods: Ninety patients were assigned at random to three groups in which induction was performed with either etomidate-lipuro, propofol or etomidate-lipuro-propofol admixture. After monitorization with bispectral index (BIS) all agents were given with infusion with a perfuser at a constant rate of 200 ml/min till the BIS values decreased to 40. Blood pressure and heart rate were measured every 30 s at this period. Patients were asked for pain at the injection site and observed visually for myoclonus. The time BIS values decreased to 40 (BIS 40 time) and total amounts of induction doses were measured. Results: BIS 40 time measurements were P > E > PE (199.4 ± 40.9, 176.9 ± 31.6, 163.5 ± 20.6 s). The hemodynamic (systolic, diastolic and mean blood pressures, heart rate) changes were minimal in group PE than other two groups (P = 0.017). The intensity of myoclonus was graded as mild in 9, moderate in 12, and severe in 5 patients in the group E (76.3%). Myoclonus was not observed in group PE and group P. There were no injection pain in group PE as the incidence were (83.8%) in group P and in (63.2%) group E. Conclusion: Incidence of hemodynamic changes, myoclonus, and injection pain is significantly lower in group PE. BIS 40 times is least in group PE. We concluded that 1:1 admixture of etomidate-lipuro and propofol is a valuable agent for induction.
ACCESSION #
58516610

 

Related Articles

  • Cardioversion: What to choose? Etomidate or propofol. Desai, Pushkar M.; Kane, Deepa; Sarkar, Manjula S. // Annals of Cardiac Anaesthesia;Jul-Sep2015, Vol. 18 Issue 3, p306 

    Context: Electrical cardioversion is a short painful procedure to regain normal sinus rhythm requiring anaesthesia for haemodynamic stability, sedation, analgesia and early recovery. Aims: To compare propofol and etomidate as sedatives during cardioversion. Settings and Design: Single centred,...

  • Cost-effectiveness of different regimens of anesthesia for day surgery in China. Liang Shen; Yan Luo; Zhijun Lu; Xiang Hu; Wen Ding; Buwei Yu // International Journal of Clinical & Experimental Medicine;2014, Vol. 7 Issue 12, p5744 

    Objectives: To compare the cost-effectiveness of inhalation of sevoflurane, target-controlled infusion (TCI) of propofol, intravenous (IV) propofol for induction-inhalation of sevoflurane, and IV propofol for induction-inhalation of desoflurane for anesthesia maintenance in day surgery. Methods:...

  • Intravenous administration sets.  // Journal of Perioperative Practice;Mar2006, Vol. 16 Issue 3, p112 

    The article identifies the optimal interval for the routine replacement of intravenous administration sets when infusate or parenteral nutrition solutions are administered to people in hospital via central or peripheral venous catheters. Intravenous administration is a common occurrence within...

  • Make room for new IVIG-this one from a foreign firm. Magill-Lewis, Jillene // Drug Topics;7/12/2004, Vol. 148 Issue 13, p36 

    This article provides information on the intravenous immune globulins (IVIG or IGIV) drug, Octagam, developed by Octapharma AG. The U.S. Food and Drug Administration approved Octapharma's IVIG product in May 2004 but the firm has been marketing the product in Europe for 10 years. Octagam is...

  • TOWARD IMPECCABLE IV TECHNIQUE. Masoorlie, Susan Thomas // RN;Feb81, Vol. 44 Issue 2, p20 

    Provides guidelines that nurses can use for veripuncture. Tips on choosing the site, vein and device; Anatomy of a vein; Steps in inserting a scalp vein needle; Procedure in inserting an intravenous catheter.

  • Bispectral index monitors, non-invasive cardiac output monitors, and haemodynamics of induction agents. Kakazu, C.; Lippmann, M. // BJA: The British Journal of Anaesthesia;Jan2014, Vol. 112 Issue 1, p169 

    No abstract available.

  • Bispectral index-guided induction of general anaesthesia. Kamenik, M.; Möller Petrun, A. // BJA: The British Journal of Anaesthesia;Jan2014, Vol. 112 Issue 1, p169 

    No abstract available.

  • SODIUM AND POTASSIUM DEHYDROCHOLATE AS DIURETIC AGENTS. Vogl, Alfred; Kaizer, Miltiades // Angiology;Apr1957, Vol. 8 Issue 2, p145 

    1. The known potentiating effect of 10 cc of a 20 per cent solution of Decholin Sodium (by intravenous injection) upon mercurial diuresis is confirmed by the studies reported here. Of 19 edematous patients, 11 showed a significant potentiating effect of Decholin Sodium on mercurial diuresis, 6 a...

  • Variability in the concentrations of intravenous drug infusions prepared in a critical care unit. Wheeler, Daniel Wren; Degnan, Beverley Ann; Sehmi, Jobanpreet Singh; Burnstein, Rowan Margaret; Menon, David Krishna; Gupta, Arun Kumar // Intensive Care Medicine;Aug2008, Vol. 34 Issue 8, p1441 

    To quantify the variability in the concentration of drug infusions prepared on an intensive care unit and establish whether there was a relationship between the quality of syringe labeling and drug preparation. Audit carried out over 3 weeks in May 2006 and completed in May 2007. The adult...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics