Radiation-Induced Mineralizing Microangiopathy in a Case of Recurrent Craniopharyngioma

Srinivasan, K. G.; Ramprabananth, S.; Ushanandhini, K. P.; Srividya, S.; Praveen Kumar, M.
August 2010
Neuroradiology Journal;Aug2010, Vol. 23 Issue 4, p412
Academic Journal
Case Study
Mineralizing microangiopathy is a late complication of radiation-induced brain in- jury that occurs during the treatment of CNS malignancies in children and adults. Early diagnosis of the radiation-induced brain injury helps to tailor the radiation dose and prevent further complications. Here we describe an operated patient with craniopharyngioma who underwent external beam radiotherapy. The patient developed gradual loss of vision after two years and a review CT scan revealed the local recurrence of tumour with dystrophic calcification of the basal ganglia, frontal and temporal subcortical regions representing recurrent craniopharyngioma with radiation-induced mineralizing microangiopathy.


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