TITLE

Acetylcholinesterase Inhibitors (AChEI's) for the treatment of visual hallucinations in schizophrenia: a case report

AUTHOR(S)
Patel, Sachin S.; Attard, Azizah; Jacobsen, Pamela; Shergill, Sukhi
PUB. DATE
January 2010
SOURCE
BMC Psychiatry;2010, Vol. 10, p68
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Background: Visual hallucinations are commonly seen in various neurological and psychiatric disorders including schizophrenia. Current models of visual processing and studies in diseases including Parkinsons Disease and Lewy Body Dementia propose that Acetylcholine (Ach) plays a pivotal role in our ability to accurately interpret visual stimuli. Depletion of Ach is thought to be associated with visual hallucination generation. AchEI's have been used in the targeted treatment of visual hallucinations in dementia and Parkinson's Disease patients. In Schizophrenia, it is thought that a similar Ach depletion leads to visual hallucinations and may provide a target for drug treatment Case Presentation: We present a case of a patient with Schizophrenia presenting with treatment resistant and significantly distressing visual hallucinations. After optimising treatment for schizophrenia we used Rivastigmine, an AchEI, as an adjunct to treat her symptoms successfully. Conclusions: This case is the first to illustrate this novel use of an AchEI in the targeted treatment of visual hallucinations in a patient with Schizophrenia. Targeted therapy of this kind can be considered in challenging cases although more evidence is required in this field.
ACCESSION #
54098143

 

Related Articles

  • Acetylcholinesterase Inhibitors (AChEI's) for the treatment of visual hallucinations in schizophrenia: A review of the literature. Patel, Sachin S.; Attard, Azizah; Jacobsen, Pamela; Shergill, Sukhi // BMC Psychiatry;2010, Vol. 10, p69 

    Background: Visual hallucinations occur in various neurological diseases, but are most prominent in Lewy body dementia, Parkinson's disease and schizophrenia. The lifetime prevalence of visual hallucinations in patients with schizophrenia is much more common than conventionally thought and...

  • Talking therapy trialled for command hallucinations. McMillan, Ian // Mental Health Practice;Feb2012, Vol. 15 Issue 5, p6 

    The article discusses research being done on cognitive behavior approaches as treatment for command hallucinations. It references the study "A Multi-Centre, Randomized Controlled Trial of Cognitive Therapy to Prevent Harmful Compliance With Command Hallucinations," by M Birchwood and colleagues...

  • Schizophrenia and Other Psychotic Disorders. de Beaurepaire, Renaud; Honig, Adriaan; Blass, John // Current Medical Literature: Psychiatry;2012, Vol. 23 Issue 3, p81 

    The article discusses studies on schizophrenia and other psychotic disorders, published in medical journals as of 2012. One study examined transcranial direct-current stimulation (tDCS) as a treatment method for hallucinations in schizophrenia. Another discussed metformin as a treatment of...

  • Hallucinations in schizophrenia. White, Adrian // Acupuncture in Medicine;Sep2010, Vol. 28 Issue 3, p156 

    The article presents a summary and commentary on the use of electro-acupuncture to treat auditory hallucinations in schizophrenic patients.

  • Public stigma and schizophrenia in São Paulo city. Peluso, Érica Toledo Piza; Blay, Sérgio Luís // Revista Brasileira de Psiquiatria;jun2011, Vol. 33 Issue 2, p130 

    Objective: To assess public stigma in relation to people with schizophrenia and possible factors associated with this phenomenon. Method: A cross-sectional study was conducted with a probabilistic sample of 500 individuals who live in the city of Sao Paulo, Brazil, and are aged between 18 and 65...

  • CONTINUING PROFESSIONAL DEVELOPMENT. Hallucinations: insights and supportive first care. Price, Bob // Nursing Standard;1/20/2016, Vol. 30 Issue 21, p49 

    Nurses working in a range of clinical settings may encounter patients who report experiencing hallucinations, whether auditory, visual or any other form. This article, which has been written for nurses working in general practice rather than mental health practice, clarifies the differences...

  • Schizophrenics Are People. Allen, John S. // Humanist;May/Jun91, Vol. 51 Issue 3, p26 

    Argues that schizophrenics have been wrongfully dehumanized. Deinstitutionalization has put them on the streets; Lack of advocacy groups; A special disease which needs to be examined in a more human, less clinical way.

  • Versión abreviada del WAIS-III para su uso en la evaluación de pacientes con diagnóstico de esquizofrenia. Durá, Inmaculada Fuentes; Pens, Maria Romero; Vivó, Carmen Dasí; Ruiz, Juan Carlos Ruiz // Psicothema;may2010, Vol. 22 Issue 2, p202 

    The aim of this study is to obtain a sufficiently guaranteed, abridged, Spanish version of the WAIS-III and thereby reduce the time needed to administer the complete scale. Although the samples used were based both on normal individuals (41 participants with no known history of mental illness)...

  • Schizophrenia researchers striving for early detection and intervention. Stephenson, Joan; Stephenson, J // JAMA: Journal of the American Medical Association;5/26/99, Vol. 281 Issue 20, p1877 

    Focuses on efforts to identify early signs of schizophrenia in high-risk individuals and to develop interventions aimed at delaying its onset or reducing severity. Diagnosis, treatment delays; Early signs; Research efforts in Australia.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics