Profound Hearing Loss Associated with Oxycodone-Acetaminophen Abuse

Rigby, Matthew H.; Parnes, Lorne S.
December 2008
Journal of Otolaryngology -- Head & Neck Surgery;Dec2008, Vol. 37 Issue 6, pE161
Academic Journal
Case Study
A case report on sensorineural hearing loss (SNHL) associated with oxycodone-acetaminophen or Percocet abuse is discussed. The rapidly progressive SNHL in this case study involves a 55-year-old female with right-sided tinnitus and profound bilateral hearing loss. The metabolisms of oxycodone and acetaminophen are examined and although they are similar, they do not have common metabolites. The study suggests that a class effect from opioids caused the hearing loss.


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