Spontaneous intracerebral haemorrhage as initial presentation of gestational choriocarcinoma in a young woman: a case report and review of literature

Singhal, Mini; Kudesia, Sandip; Bhat, Kiran; Arora, Pankaj; Sharma, Arti
January 2010
Internet Journal of Pathology;2010, Vol. 10 Issue 2, p4
Academic Journal
Case Study
Choriocarcinoma is the most malignant tumor of gestational trophoblastic tissue with a tendency to early metastasis. We report a case of metastatic cerebral choriocarcinoma in a 23 year old female with appearance of acute neurological signs following spontaneous intracerebral haemorrhage as the initial presentation. The diagnosis was established by histopathological examination of the blood clots and confirmed by a high serum beta human chorionic gonadotrophin (HCG) level. However; the patient did not have any evidence of the tumour elsewhere. The case emphasizes the importance of suspecting an underlying choriocarcinoma and measuring serum beta HCG level in women of child bearing age group presenting with spontaneous cerebral haemorrhage.


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