TITLE

Early onset primary pulmonary cryptococcosis in a renal transplant patient

AUTHOR(S)
Tarai, B.; Kher, V.; Kotru, P.; Sabhikhi, A.; Barman, P.; Rattan, A.
PUB. DATE
July 2010
SOURCE
Indian Journal of Medical Microbiology;Jul2010, Vol. 28 Issue 3, p250
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
We report a case of primary pulmonary cryptococcosis in a postrenal transplant patient. A 65-year-old male renal transplant patient was admitted to the hospital with a low grade fever of 1 month, radiologically mimicking tuberculosis (TB). Broncho-alveolar fluid (BAL) shows capsulated yeast, and Cryptococcus neoformans was grown on culture supported by cytology and histopathological examination. Cryptococcal antigen was positive (32-fold) in serum and was negative in cerebrospinal fluid (CSF). The patient was given amphotericin B and 5-flucytosine and clinical improvement was seen on a weekly follow up. The serum cryptococcal antigen test might contribute to the early detection and treatment of pulmonary cryptococcosis. The results of antifungal susceptibility were aid in selecting the drug of choice for treatment.
ACCESSION #
52597062

 

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