The Use of rhBMP-2 for the Treatment of Congenital Pseudarthrosis of the Tibia: A Case Series

Richards, B. Stephens; Oetgen, Matthew E.; Johnston, Charles E.
January 2010
Journal of Bone & Joint Surgery, American Volume;Jan2010, Vol. 92-A Issue 1, p177
Academic Journal
Case Study
The article presents a case study of seven patients in which recombinant human bone morphogenetic protein (rhBMP-2) was used in addition to the intramedullary rod technique for the treatment of congenital pseudarthrosis of the tibia. It examines if any detrimental effects secondary to the use of rhBMP-2 became clinically apparent in patients over a minimum duration of follow-up of four years. The study found that the addition of rhMP-2 would improve the radiographic union rate of pseudarthrosis.


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