A Case of Cerebral Hypoxia with Co-existing Corpus Callosum Agenesis and Colpocephaly Manifesting as Mild Mental Retardation

Mourgela, Sofia; Anagnostopoulou, Sofia; Sakellaropoulos, Antonios; Gazelopoulou, Irini
March 2009
Journal of Neurological Sciences;2009, Vol. 26 Issue 1, p79
Academic Journal
Case Study
This is the case of a 9-year old female patient who initially had been admitted in the pediatric hospital "Agia Sofia" as a newborn, because of severe brain hypoxia, due to persistent fetal circulation. Then, at the age of 3 years, she had been managed in the same hospital, because of an episode of febrile tonic-clonic spasms. Brain CT revealed total absence of the corpus callosum and colpocephaly. The clinical picture of the child is that of mild mental retardation accompanied by epileptic attacks, although the coexistent agenesis of the corpus callosum and colpocephaly. From this case, we conclude that these pathological entities may have no cumulative effect on the clinical picture of a patient when they coexist.


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