2007 - Review: Primary prophylaxis with banding ligation or beta-blockers does not differ for mortality in esophageal varices

Korula, Jacob
May 2008
ACP Journal Club;5/20/2008, Vol. 148 Issue 3, p9
Academic Journal
Case Study
The article focuses on a case study that was conducted to compare the effects of primary prophylaxis with banding ligation (BL) and β-blockers in patients with esophageal varices and no previous history of bleeding. The study found that BL and β-blockers did not differ for all-cause mortality or bleeding-related mortality.


Related Articles

  • Earlier recurrence of esophageal varices, following therapy, in patients with primary biliary cirrhosis (PBC) compared with non-PBC patients. Takeshita, Eiji; Matsui, Hidetaka; Shibata, Naozumi; Furukawa, Shinya; Yokota, Tomoyuki; Murakami, Hidehiro; Ikeda, Yoshiou; Hiasa, Yoichi; Matsuura, Bunzo; Michitaka, Kojiro; Onji, Morikazu // Journal of Gastroenterology;2004, Vol. 39 Issue 11, p1085 

    Background. Variceal bleeding is a common, lifethreatening complication of primary biliary cirrhosis (PBC). Recently, several reports have suggested that the existence of esophageal varices in patients with PBC is a significant factor in the assessment of disease prognosis. However, there have...

  • Endoscopic clipping versus band ligation in the management of bleeding esophageal varices. Yol, S.; Belviranli, M.; Toprak, ?.; Kartal, A. // Surgical Endoscopy;Jan2003, Vol. 17 Issue 1, p38 

    Background: The effectiveness of endoscopic clipping in the hemostasis of bleeding esophageal varices and the eventual variceal eradication was compared with that of band ligation. Methods: Forty patients were enrolled in the study in a prospective manner, 19 of whom received endoscopic clipping...

  • Gross and Microscopic Findings in the Human Esophagus after Esophageal Variceal Band Ligation: A Postmortem Analysis. Marks, Robert D.; Arnold, Muoi D.; Baron, Todd H. // American Journal of Gastroenterology;Feb1993, Vol. 88 Issue 2, p272 

    Endoscopic sclerotherapy has been the therapy of choice for controlling acute variceal hemorrhage. Recently, endoscopic band ligation has been utilized for the management of esophageal varices with fewer complications and greater efficacy. We report the pathologic findings in the human esophagus...

  • Endoscopic Injection Sclerotherapy for Esophageal Varices Using a Transparent Hood. Horigome, Hideo; Nomura, Tomoyuki; Nakao, Haruhisa; Kanematsu, Takayoshi; Joh, Takashi; Ohara, Hirotaka // American Journal of Gastroenterology;Dec2000, Vol. 95 Issue 12, p3679 

    Discusses the use of transparent hood in the administration of endoscopic injection sclerotherapy (EIS) for esophageal varices. Description of the administration of EIS; Comparison of EIS with endoscopic variceal ligation; Advantages of using transparent hood in the administration of EIS.

  • Continuous Low Dose Peripheral Vein Pitressin Infusion in the Control of Variceal Bleeding. Rigberg, Leon A.; Ufberg, Michael H.; Brooks, Charles M. // American Journal of Gastroenterology;Nov1977, Vol. 68 Issue 5, p481 

    Continuous low dose peripheral vein pitressin has been shown to be effective in controlling variceal bleeding in seven episodes of bleeding in six patients. No significant side-effects were seen. The expense, delay and hazard associated with superior mesenteric artery catheterization for...

  • Does gastroesophageal reflux have an influence on bleeding from esophageal varices? Okamoto, Eisuke; Amano, Yuji; Fukuhara, Hiroyuki; Furuta, Koichiro; Miyake, Tatsuya; Sato, Shuichi; Ishihara, Shunji; Kinoshita, Yoshikazu // Journal of Gastroenterology;2008, Vol. 43 Issue 10, p803 

    Mucosal breaks induced by gastroesophageal reflux of gastric contents were more frequently found on the right anterior wall of the lower esophagus. Bleeding from esophageal varices may be also derived from gastroesophageal reflux. The circumferential location of the ruptured esophageal varices...

  • DOES SIZE MATTER: HOW BEST TO SEE TO BELIEVE? Richards, Robert J.; Minocha, Anil; Johnson, David // American Journal of Gastroenterology;Mar1997, Vol. 92 Issue 3, p536 

    Reviews the study "Comparison of High-Resolution Endoluminal Sonography to Video Endoscopy in the Detection and Evaluation of Esophageal Varices," by L. S. Miller, T. D. Schiano, A. Adrian, et al., published in the 1996 issue of the "Hepatology."

  • β-BLOCKERS AND PREVENTION OF FIRST VARICEAL HEMORRHAGE: TANTALIZING EXPECTATIONS? Selub, Steven; Barkin, Jamie S.; Johnson, David A.; Cattau Jr., Edward L. // American Journal of Gastroenterology;Dec1992, Vol. 87 Issue 12, p1880 

    Comments on a study on the efficacy of propranolol in preventing the initial hemorrhage from esophagogastric varices by Conn H. O et al, published in a 1991 issue of "Hepatology." Abstract of the study; Key findings; Criticisms.

  • VARICEAL HEMORRHAGE--TO BLOCK OR NOT TO BLOCK? Carey, William F.; Johnson, David A.; Cattau, Edward // American Journal of Gastroenterology;Jun1990, Vol. 85 Issue 6, p757 

    Discusses a study on variceal hemorrhage. Methods applied in the study; Mortality rate from bleeding varices; Use of beta-blockade to reduce portal pressure via mechanisms that are quite complex and related not only to the cardiac effects of these drugs; Factors that influence the occurrence of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics