TITLE

Growing PET positive nodule in a patient with histoplasmosis: case report

AUTHOR(S)
Salhab, Khaled F.; Baram, Daniel; Bilfinger, Thomas V.
PUB. DATE
January 2006
SOURCE
Journal of Cardiothoracic Surgery;2006, Vol. 1, p23
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Background: Pulmonary histoplasmosis is a mycotic infection that often resembles pulmonary malignancy and continues to complicate the evaluation of pulmonary nodules. Case presentation: We report a case of an immunocompetent patient who, despite adequate treatment for known histoplasmosis lung infection, presented with radiological and F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) findings mimicking primary lung malignancy which eventually required surgical resection. Conclusion: Histoplasmosis infection may radiologically resemble pulmonary malignancy, often causing a diagnostic dilemma. PET imaging is currently used for and considered accurate in the evaluation of pulmonary nodules. However, overlap in PET standardized uptake value (SUV) between granulomatous and malignant lesions decreases the accuracy of PET as a diagnostic modality. Future advances in PET imaging are needed to improve its accuracy in the evaluation of pulmonary nodules in areas where histoplasmosis is endemic.
ACCESSION #
30093738

 

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