Phrynoderma: a cutaneous sign of an inadequate diet

Di Stefani, Alessandro; Orlandi, Augusto; Chimenti, Sergio; Bianchi, Luca
October 2007
CMAJ: Canadian Medical Association Journal;10/9/2007, Vol. 177 Issue 8, p855
Academic Journal
Case Study
The article presents the case studies of a 28-year-old man with a 6- month history of diffuse and slightly pruritic papules and a 23-year-old man with an 8-month history of intensely pruritic lesions on his trunk and on the extensor surfaces of his extremities. The clinical differential diagnoses in both cases included phrynoderma, prurigo nodularis, follicular lichen planus, Kyrle's disease and Besnier's prurigo. Phrynoderma is a form of follicular hyperkeratosis that is associated with nutritional deficiencies.


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