Sevoflurane Anaesthesia in a Patient with Renal Transplantation: Case Report and Literature Review

Eroglu, Ahmet; Erturk, Engin; Bostan, Habib; Trabzon Turkey
July 2007
Internet Journal of Anesthesiology;2007, Vol. 13 Issue 2, p17
Academic Journal
Case Study
In this case report, we have presented our anaesthetic management in a patient undergoing urgent abdominal surgery who has undergone renal transplantation before, and has been in a chronic haemodialysis program two times a week. Anaesthesia was induced with sevoflurane in nitrous oxide-oxygen mixture via a mask and maintained with sevoflurane 1.5% in N2O:O2 (50%:50%). A bolus dose of atracurium 25 mg was administered intravenously and intubation was done. Standard monitoring consisted of an electrocardiogram, non-invasive arterial pressure and pulse oximetry. Serum creatinine, potassium, sodium and blood urea nitrogen levels and also creatinine clearance were measured preoperatively and in the first, second, third and seventh postoperative days. Surgical cholecystectomy was performed and the duration of anaesthesia was 60 minutes. We conclude that sevoflurane does not aggravate renal impairment in measured parameters (serum creatinine, blood urea nitrogen and creatinine clearense) of renal function and does not change the time for haemodialysis in the patient with renal insufficiency.


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