Case 35-2006

Brown, Robert H.; Grant, P. Ellen; Pierson, Christopher R.
November 2006
New England Journal of Medicine;11/16/2006, Vol. 355 Issue 20, p2132
Academic Journal
Case Study
The article describes the case of a newborn boy who was admitted to a special care nursery because of hypotonia. Magnetic resonance imaging (MRI) of the brain showed a region of polymicrogyria involving the medial right temporal and occipital lobes. The infant, while breathing ambient air in an open crib, remained in hemodynamically stable condition. It is believed the most likely diagnosis was a congenital muscular dystrophy, probably caused by severe merosin deficiency that is either primary or secondary.


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