Calcific Uremic Arteriolopathy (Calciphylaxis)

Rifkin, Brian S.; Perazella, M. A.
January 2006
Mayo Clinic Proceedings;Jan2006, Vol. 81 Issue 1, p9
Academic Journal
Case Study
The article presents a case study involving a 61-year-old man who was diagnosed as having calcific uremic arteriolopathy (CUA). Suffering from diabetes mellitus for 25 years and renal failure, he was hospitalized and was injected with low-dose warfarin prophylaxis. Four months later, he presented with a presumed penile infection, and one month later, he returned with complaints of tenderness and a violet rash on the lateral aspect of both thighs. Skin biopsy findings indicated he was suffering from CUA, while Histopathologic studies showed thrombi within arterioles and intimal calcification. Risk factors for CUA include elevated phosphorus levels, increased body mass index, and hypoalbuminemia.


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