A phenomenal response to treatment by an advanced tumour

Spiller, Robin; Rahman, S. H.; Roy, A.; Leahy, M.; Guillou, P. J.; Toogood, G. J.
December 2004
Gut;Dec2004, Vol. 53 Issue 12, p1582
Academic Journal
Case Study
This article focuses on a case study that deals with a phenomenal response to treatment by an advanced tumor. The case has been presented as a quiz for medical practitioners. A 44 year old woman presented with a longstanding history of epigastric pain, weight loss, and dysphagia. Upper gastrointestinal duodenoscopy demonstrated an 8 cm infiltrating tumor of the proximal stomach, and biopsy of the lesion demonstrated a necrotic solid tumor with a predominant epithelioid morphology arranged in small solid clusters with multiple scattered mitotic figures. Immunohistochemical staining revealed strong expression of vimentin, CD34, and c-kit in virtually all tumor cells. The article now asks about the treatment options for the patient.


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