Case study: cerebrovascular parkinsonism with levodopa addiction

Lity, O; Al-Din, A
September 2004
Journal of Neurology, Neurosurgery & Psychiatry;Sep2004, Vol. 75 Issue 9, p1365
Academic Journal
Case Study
Levodopa, the mainstay of treatment for idiopathic Parkinson's disease, has a mild stimulant effect and may cause agitation, restlessness and euphoria even in normal subjects. It is associated with a well documented withdrawal syndrome consisting of confusion, muscular pain and rigidity. This can progress to involve symptoms comparable with neuroleptic malignant syndrome, including pyrexia and increased creatine kinase. The article focuses on a 81 year old woman had been diagnosed with Parkinson's disease 10 years before.


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