TITLE

Pulmonary langerhans cell histiocytosis: Two cases with varied radiologic findings

AUTHOR(S)
Gunbatar, Hulya; Yavuz, Alpaslan; Sertogullarindan, Bunyamin; Ekin, Selami; Asker, Selvi; Sayır, Fuat; Bayram, Irfan
PUB. DATE
January 2016
SOURCE
Eastern Journal of Medicine;2016, Vol. 21 Issue 1, p45
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Pulmonary Langerhans Cell Histiocytosis (PLCH) is an idiopathic interstitial lung disease with Langerhans cell infiltration in the lung. PLCH X has non-spesific symptoms, and most patients have smoking history. A combination of stellate nodules, reticular and nodular opacities, upper zone cysts or honeycombing, preservation of lung volume and costophrenic angle sparing are highly specific for PLCH. To contribute to the literature, two cases are presented. First case is 30 years old man with 10 pack/years smoking history was admitted with cough and persevering interstitial opacities. Second case is 34 years old man with 15 pack/years smoking history was admitted with persistant cough. On thorax CT the first case had reticulonodular opacities at the perifery of the upper and middle zones, second case had multiple parenchymal cystic nodular lesions. Open lung biopsy performed, immunohistochemical examination CD1a, CD68, S100 detecting antigenpositive and histologically and radiologically confirmed diagnosed of PLCH.
ACCESSION #
122920920

 

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