TITLE

Ameloblastic carcinoma: An analysis of 12 cases with a review of the literature

AUTHOR(S)
JIA LI; HONGMING DU; PENG LI; JINGKUI ZHANG; WEIDONG TIAN; WEI TANG
PUB. DATE
August 2014
SOURCE
Oncology Letters;2014, Vol. 8 Issue 2, p914
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
The diagnosis of ameloblastic carcinoma is often difficult and the optimal treatment methods remain controversial. The current study retrospectively investigated the optimal diagnosis and treatment methods of 12 ameloblastic carcinoma patients at the West China Hospital of Stomatology, Sichuan University (Chengdu, China), and 20 patients selected from the PubMed database, were reviewed. The clinical features, diagnosis and outcome of the different treatments were evaluated. Ameloblastic carcinoma occurred in 12 out of a total of 538 ameloblastoma patients; the majority were of the primary type. Of the 538 ameloblastoma patients, 294 were male, 244 were female with a male to female ratio of 1.2:1. The predilection age is 20-30 years, which accounts for 40% of the total. In total, 461 cases were in the mandible and 77 were located in the maxilla. The cure rate of the primary type and the recurrence rate of the secondary type tumors were higher in the patients from the West China Hospital of Stomatology compared with those reported in the literature. In particular, a case with a long-term survival of 30 years is presented, which is considered to be relatively rare. The evolution of the clinical course has experienced three stages: Ameloblastoma (1978) followed by metastatic ameloblastoma (2000) and finally ameloblastic carcinoma (2008). To avoid recurrence, wide local excision with postoperative radiation therapy is required. While novel therapeutic regimens should also be considered as appropriate, including carbon ion therapy and Gamma Knife stereotactic radiosurgery. However, controlled studies with larger groups of patients are required to increase the accuracy of results.
ACCESSION #
110397838

 

Related Articles

  • Wide Surgical Excision with Split Rib Graft Reconstruction of Mandible for Ameloblastoma; Our 10 Year Experience. Ahmad, Imran; Choudhary, Rampukar // Indian Journal of Otolaryngology & Head & Neck Surgery;Jan2013, Vol. 65 Issue 1, p40 

    Ameloblastoma or adamantinoma is a benign odontogenic tumour arising in facial bones mostly in mandible. There are different modalities of treatment for ameloblastoma viz. chemotherapy, radiation therapy, curettage and liquid nitrogen but surgical resection or enucleation remains the most...

  • Metastasizing Ameloblastoma With Localized Interstitial Spread in the Lung: Report of Two Cases. Chou, Yueh-Hung; Jhuang, Jie-Yang; Chang, Min-Hsiang; Huang, Wen-Chih; Hsieh, Min-Shu // International Journal of Surgical Pathology;Jun2014, Vol. 22 Issue 4, p343 

    Ameloblastoma is a locally aggressive, epithelial odontogenic tumor involving mandibles and maxillas. Distant metastasis is a very rare condition and is designated as metastasizing (malignant) ameloblastoma despite its benign histological appearance. Up to now, only 27 well-documented cases of...

  • Métastase mandibulaire d'un carcinome folliculaire de la thyroïde : un cas rare après 7 ans. Khalfi, Lahcen; Ziani, Yassine; Oukabli, Mohammed; Nassih, Mohammed; Abouchadi, Abdeljalil; El Khatib, Karim // Médecine Buccale Chirurgie Buccale;2014, Vol. 20 Issue 3, p189 

    Introduction: Mandibular metastasis represents only 1% of malignant oral cavity tumors. Case report: We report a case of a mandibular tumor without metastasis. The patient was operated on, 7 years ago, for follicular thyroid carcinoma. Tumor resection with mandibular reconstruction was...

  • Treatment of huge mandible mural ameloblastoma by modified transoral radical curettage. GUO Ji-ming; CHEN Zheng-gang; QIU Jian-zhong; ZHOU Jian-hua; WANG Ke-tao; DONG Zuo-qing // China Journal of Oral & Maxillofacial Surgery;Mar2011, Vol. 9 Issue 2, p151 

    PURPOSE: To evaluate the effectiveness of modified transoral radical curettage on treatment of huge mandibular mural ameloblastoma. METHODS: Eighteen patients with huge mandibular mural ameloblastoma were selected and followed up for 3 months to 5 years after modified transoral radical...

  • Large ameloblastic carcinoma: A rare case with management. Augustine, Dominic; Sekar, B.; Murali, S. // Dental Research Journal;Nov2013, Vol. 10 Issue 6, p809 

    The ameloblastic carcinoma is a rare malignant counterpart of the ameloblastoma. Ameloblastic carcinoma is a malignant lesion with characteristic histologic features and behavior that dictates a more aggressive surgical approach than that of a simple ameloblastoma. However, reliable evidence of...

  • Pulmonary metastasectomy in the treatment of recurrent ameloblastoma of the maxilla and mandible: a case report. Önerci, Metin; Yilmath;lmaz, Taner; Dogan, Riza; Sungur, Arzu // European Archives of Oto-Rhino-Laryngology;Jan2001, Vol. 258 Issue 1, p25 

    Ameloblastoma is an aggressive benign tumor with frequent local recurrences. Although histologically benign, it occasionally metastasizes to many organs, most commonly to the lungs. The metastasis develops after multiple recurrences and many unsuccessful attempts at removal of the tumor. When...

  • Ameloblastic carcinoma of the mandible. Purmal, K.; Alam, M. K.; Pohchi, A.; Rahman, S. A. // Bangladesh Journal of Medical Science;Apr2015, Vol. 14 Issue 2, p196 

    Ameloblastic carcinoma is a highly malignant tumour and requires aggressive treatment. This case report describes an aggressive ameloblastic carcinoma that infiltrated the mandible. Mandibulectomy with right functional radical neck dissection and left supra omohyoid dissection was followed by...

  • Prostatic carcinoma metastatic to the paranasal sinuses: A case report. Viswanatha, Borlingegowda // ENT: Ear, Nose & Throat Journal;Sep2008, Vol. 87 Issue 9, p519 

    In the paranasal sinuses, metastatic carcinoma is far less common than primary carcinoma. Metastasis of prostate cancer to the paranasal sinuses is very rare. The author describes a case of prostatic adenocarcinoma that metastasized to the frontal and ethmoid sinuses in a 68-year-old man. The...

  • An unusual case of isolated, serial metastases of gallbladder carcinoma involving the chest wall, axilla, breast and lung parenchyma. Jeyaraj, Pamela; Sio, Terence T.; Iott, Matthew J. // Rare Tumors;2013, Vol. 5 Issue 1, p27 

    In the English literature, only 9 cases of adenocarcinoma of the gallbladder with cutaneous metastasis have been reported so far. One case of multiple cutaneous metastases along with deposits in the breast tissue has been reported. We present a case of incidental metastatic gallbladder carcinoma...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics