Leiomyosarcoma metastatic to the cervical spine causing a C6 compression fracture: A case report

July 2014
Oncology Letters;2014, Vol. 8 Issue 1, p263
Academic Journal
Case Study
Leiomyosarcoma is a rare malignant tumor derived from smooth muscle cells, which commonly metastasizes to the lungs, liver, kidney, brain and skin. The current study presents the case of a 42-year-old male who presented with progressive neck pain and numbness of the left arm. Spinal computed tomography and magnetic resonance imaging revealed osteolytic lesions of numerous vertebrae (C2, C3, C4, C5, C6, C7, T1 and T2). With regard to the C6 vertebra, total destruction of the vertebral body resulted in vertebral collapse and subsequent spinal cord compression. The patient underwent an anterior C6 corpectomy, reconstruction with a mesh cage filled with polymethyl methacrylate (PMMA) and open PMMA infusion to C5 and C7. The surgical procedure significantly alleviated the symptoms and obtained a reliable reconstruction. The clinical follow-up examination at 13 months was uneventful with the exception of mild numbness of the left hand since the surgery. To the best of our knowledge, this is the first case of leiomyosarcoma recurrence presenting in the cervical spine, and the present study provides insight into the use of a surgical technique that has rarely been used in the cervical spine.


Related Articles

  • Management of the neglected and healed bilateral cervical facet dislocation. Srivastava, Abhishek; Soh, Reuben; Ee, Gerard; Tan, Seang; Tow, Benjamin // European Spine Journal;Aug2014, Vol. 23 Issue 8, p1612 

    Introduction: There is limited literature on the management of neglected healed (fused) bilateral cervical facet dislocation. The authors report a case of a middle aged male who developed a bilateral facet dislocation but only sought treatment 14 months post injury when he experienced pain and...

  • Emergency CT head and neck imaging: effects of swimmer's position on dose and image quality. Mueck, Fabian; Roesch, Sebastian; Geyer, Lucas; Scherr, Michael; Seidenbusch, Michael; Stahl, Robert; Deak, Zsuzsanna; Wirth, Stefan // European Radiology;May2014, Vol. 24 Issue 5, p969 

    Objectives: To compare the effects of different arm positions on dose exposure and image quality (IQ) in cervical spine CT after trauma in different patient groups. Methods: Patients in standard (STD = 126) and in swimmer's position (SWIM = 254) were included. Body mass index (BMI subgroup 1 =...

  • Differential diagnosis of uterine smooth muscle tumors using diffusion-weighted imaging: correlations with the apparent diffusion coefficient and cell density. Tasaki, Akiko; Asatani, Mina; Umezu, Hajime; Kashima, Katsunori; Enomoto, Takayuki; Yoshimura, Norihiko; Aoyama, Hidefumi // Abdominal Imaging;Aug2015, Vol. 40 Issue 6, p1742 

    The purpose of this study is to investigate the utility of the apparent diffusion coefficient (ADC) in differentiating benign and malignant uterine smooth muscle tumors classified by signal intensity (SI) on T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI), and to determine the...

  • Hemangiopericytomas of the spine: case report and review of the literature. Cole, Chad D.; Schmidt, Meic H. // Rare Tumors;2009, Vol. 1, p132 

    We describe a rare case of a primary intracranial meningeal hemangiopericytoma (HPC) with late metastasis to the cervical spine. A 36-year-old woman had a left occipital lesion that was histopathologically identified as HPC. Fourteen years after resection, the tumor recurred and was treated with...

  • Cervical Symmetric Dumbbell Ganglioneuromas Causing Severe Paresis. Hioki, Akira; Miyamoto, Kei; Hirose, Yoshinobu; Kito, Yusuke; Fushimi, Kazunari; Shimizu, Katsuji // Asian Spine Journal;Feb2014, Vol. 8 Issue 1, p74 

    We report an extremely rare case with bilateral and symmetric dumbbell ganglioneuromas of the cervical spine in an elderly patient. A 72-year-old man came by ambulance to our hospital due to progressive incomplete paraplegia. Magnetic resonance imaging demonstrated bilateral symmetric dumbbell...

  • Prospective Evaluation of Intrahepatic Microscopic Occult Tumor Foci in Patients with Numerous Colorectal Liver Metastases. Vigano, Luca; Di Tommaso, Luca; Mimmo, Antonio; Sollai, Mauro; Cimino, Matteo; Donadon, Matteo; Roncalli, Massimo; Torzilli, Guido // Digestive Surgery;Jul2019, Vol. 36 Issue 4, p340 

    Background: Patients with numerous colorectal liver metastases (CLM) have high risk of early recurrence after liver resection (LR). The presence of intrahepatic occult microscopic metastases missed by imaging has been hypothesized, but it has never been assessed by pathology analyses. Methods:...

  • Occurrence and Significance of Odontoid Lateral Mass Interspace Asymmetry in Trauma Patients. Billmann, Franck; Bokor-Billmann, Therezia; Burnett, Claude; Kiffner, Erhard // World Journal of Surgery;Aug2013, Vol. 37 Issue 8, p1988 

    Background: The odontoid lateral mass interspace (OLMI) is the space between the lateral aspect of the dens axis and the medial circumference of the massa lateralis atlantis. The position of OLMI asymmetry as a normal variant or pathologic finding is an area of debate and clinical interest in...

  • Rectus abdominalis muscle metastasis from uterine leiomyosarcoma: An unusual case and review of the literature. Güngör, Tayfun; Akbay, Serap; Aksüt, Hayri; Yılmaz, Bülent // Journal of the Turkish-German Gynecological Association;Jun2014, Vol. 15 Issue 2, p122 

    Uterine leiomyosarcoma is an aggressive malignancy. Spread to the lung, thyroid, liver, brain, pancreas, heart, duodenum, breast, vagina, sub-mandibular gland, and bone has been reported. We describe a case of metastatic uterine leiomyosarcoma to the rectus abdominalis muscle as the first case...

  • Adult paratesticular leiomyosarcoma. A clinical and pathological case report. Pupca, G.; Daminescu, L.; David, S.; Iacob, Mihaela; Bucuraş, V. // Romanian Journal of Urology;2014, Vol. 13 Issue 1, p48 

    Purpose: Paratesticular leiomyosarcoma is a rare malignant tumor in an adult patient that must be known by the urologist in order to adopt the most appropriate treatment. Materials and methods: We present the case of 71 years old man with a right malignant paratesticular tumor, without inguinal,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics