TITLE

Glomus tumor of the shoulder: A case report and review of the literature

AUTHOR(S)
PROIETTI, AGNESE; ALÌ, GRETA; QUILICI, FRANCESCA; BERTOGLIO, PIETRO; MUSSI, ALFREDO; FONTANINI, GABRIELLA
PUB. DATE
August 2013
SOURCE
Oncology Letters;2013, Vol. 6 Issue 4, p1021
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Glomus tumors are benign neoplasms that arise from neuromyoarterial glomus bodies, with clinical manifestations that include acute pain, cold intolerance and tenderness. Glomus tumors may occur anywhere in the skin, soft tissue or gastrointestinal tract, but are most frequently encountered in the nail bed of the hands. The present study reports the case of a 30-year-old female with a history of shoulder pain caused by a cystic neoformation. Following surgery, a microscopic examination revealed nests of small cells of a rounded and regular shape. The tumor cells exhibited positive expression for CD34 and smooth muscle actin. This study supports and confirms the fact that a glomus tumor is a benign neoplasm that may occur in multiple locations. Therefore, the significance of a histological and immunohistochemical approach for a correct characterization of this lesion is required.
ACCESSION #
110397644

 

Related Articles

  • Deregulation of HIF1-alpha and hypoxia-regulated pathways in hepatocellular carcinoma and corresponding non-malignant liver tissue–influence of a modulated host stroma on the prognosis of HCC. Simon, Frank; Bockhorn, Maximilian; Praha, Christian; Baba, Hideo A.; Broelsch, Christoph E.; Frilling, Andrea; Weber, Frank // Langenbeck's Archives of Surgery;Apr2010, Vol. 395 Issue 4, p395 

    The aim of this study was to elucidate the role of HIF1A expression in hepatocellular carcinoma (HCC) and the corresponding non-malignant liver tissue and to correlate it with the clinical outcome of HCC patients after curative liver resection. HIF1A expression was determined by quantitative...

  • Cancer genetics: A wake-up call. Skipper, Magdalena // Nature Reviews Genetics;Jul2003, Vol. 4 Issue 7, p488 

    Provides information on the findings of a study regarding the implications of gene expression in the original tumor for the development of metastasis. Genetic and epigenetic changes of a cancer cell; Nature and dynamics of genetic changes that underlie systemic cancer progression; Differences...

  • Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients.  // BMC Cancer;2012, Vol. 12 Issue 1, p131 

    The article presents the findings of a research conducted to examine the prognostic impact of messenger (mRNA) levels of osteopontin (OPN)splice variants in soft tissue sarcoma (STS) patients. It discusses the methodology of the research. It concludes that mrna expression levels of OPN slice...

  • Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients. C. Braconi; R. Bracci; I. Bearzi; F. Bianchi; S. Sabato; A. Mandolesi; L. Belvederesi; S. Cascinu; N. Valeri; R. Cellerino // Annals of Oncology;Jul2008, Vol. 19 Issue 7, p1293 

    Background: The expression of the insulin-like growth factor (IGF) system has never been studied in gastrointestinal stromal tumors (GISTs). Patients and methods: We studied the immunohistochemical expression of IGF1 receptor (IGFR-I), IGF1 and IGF2 in 94 samples of GISTs. IGF1 and IGF2...

  • Gastric Glomus Tumour: A Rare Cause of Gastrointestinal Bleeding. SAHNI, TUSHAR; LIPI, LIPKA; MISHRA, PANKAJ; GAJENDRA, SMEETA; SACHDEV, RITESH // Journal of Clinical & Diagnostic Research;Oct2015, Vol. 9 Issue 10, p1 

    A case study of 62-year-old man is presented with complaints of haematemesis and maleana, who was diagnosed with gastric glomus tumour, a cause of gastrointestinal bleeding.

  • "Pink glow": A new sign for the diagnosis of glomus tumor on ultraviolet light dermoscopy. Thatte, Sarvesh S.; Chikhalkar, Siddhi B.; Khopkar, Uday S. // Indian Dermatology Online Journal;2015 Supplement, Vol. 6, pS21 

    Glomus tumors are usually benign hamartomas, which are painful, small, and uncommon. They are usually subungal in location but may occur at other sites. A female patient presented to the outpatient department with painful swelling over the nail matrix of her right index finger. Here, we describe...

  • Assessment of Cytokeratin-19 Gene Expression in Peripheral Blood of Breast Cancer Patients and Breast Cancer Cell Lines. Keyvani, Saeideh; Karimi, Nasrin; Orafa, Zahra; Bouzari, Saeid; Oloomi, Mana // Biomarkers in Cancer;2016, Issue 8, p57 

    Detection of cytokeratin-19 (CK19) expression as an epithelial-specific marker in circulating tumor cells (CTCs) of breast cancer patients can be important for diagnostic purposes. Comparison of CK19 expression in breast cancer cell lines can indicate that expression of this marker is different...

  • Stromal microenvironment processes unveiled by biological component analysis of gene expression in xenograft tumor models. Yang, Xinan; Lee, Younghee; Huang, Yong; Chen, James L.; Xing, Rosie H.; Lussier, Yves A. // BMC Bioinformatics;2010 Supplement 9, Vol. 11, p1 

    Background: Mouse xenograft models, in which human cancer cells are implanted in immune-suppressed mice, have been popular for studying the mechanisms of novel therapeutic targets, tumor progression and metastasis. We hypothesized that we could exploit the interspecies genetic differences in...

  • Livin abrogates apoptosis of SPC-A1 cell by regulating JNKI signaling pathway. Yu-Sheng Chen; Hong-Ru Li; Ming Lin; Gang Chen; Bao-Song Xie; Neng-Luan Xu; Li-Fang Lin // Molecular Biology Reports;Jun2010, Vol. 37 Issue 5, p2241 

    Livin, a novel member of inhibitors of apoptosis protein, is highly expressed in tumor tissues. It is a potential target in tumor therapy. Silencing its gene expression has been found to promote tumor cell apoptosis or increase tumor sensitivity to therapies. This paper studied the effect of...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics