TITLE

Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature

AUTHOR(S)
GIULIA MARVASO; AGNESE BARONE; CATERINA VACCARO; VICENTE BRUZZANITI; SILVIA GRESPI; VALERIO SCOTTI; CATALDO BIANCO
PUB. DATE
August 2013
SOURCE
Oncology Letters;2013, Vol. 6 Issue 4, p897
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
The aims of radiotherapeutic treatment of brain metastases include maintaining neurocognitive function and improvement of survival. Based on these premises, we present a case report in which the role of repeat stereotactic radiosurgery (SRS) was investigated in a patient with a recurrent brain metastasis from non-small cell lung cancer in the same area as previously treated with radiosurgery. A 40-year-old male caucasian patient was diagnosed with brain metastasis from non-small cell lung cancer (NSCLC) and underwent SRS. The patient developed a recurrence of the disease and a second SRS on the same area was performed. After 8 months, tumor restaging demonstrated a lesion compatible with a recurrence and the patient underwent surgery. Histological diagnosis following surgery revealed only the occurrence of radionecrosis. Radiotherapy was well-tolerated and no grade 3/4 neurological toxicity occurred. To date, no consensus exists on the efficacy of retreatment with SRS. Despite the limited number of studies in this field, in the present case report, we outline the outcomes of this unconventional approach.
ACCESSION #
110397620

 

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