TITLE

Amphotericin B Resistant Apophysomyces elegans Causing Rhino-oculo-Cerebral Mucormycosis in an Immunocompetent Host

AUTHOR(S)
BISWAS, DEBASIS; KOTWAL, AARTI; KAKATI, BARNALI; AHMAD, SOHAIB
PUB. DATE
August 2015
SOURCE
Journal of Clinical & Diagnostic Research;Aug2015, Vol. 9 Issue 8, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Case Study
ABSTRACT
Mucormycosis, an angioinvasive infection is caused by the ubiquitous filamentous fungi of the order Mucorales and class Mucormycetes. Reports of this disease are on the rise over the past few decades. Rhino-oculo-Cerebral presentation associated with uncontrolled diabetes is the predominant characteristic of this entity. We report here a case of rhinooculocerebral mucormycosis (ROCM) due to Apophysomyces elegans (A. elegans) in a 45-year-old diabetic lady with background illness of hypothyroidism and polyradiculoneuropathy. Though this condition is usually managed with surgical debridement of the affected tissue and medical therapy with Amphotericin B, the isolate recovered in our case was found to be resistant to Amphotericin B.
ACCESSION #
110182392

 

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