Bugs and bleeding varices (Book)

June 2004
Gut;Jun2004, Vol. 53 Issue 6, p911
Book Review
This article focuses on a study related to antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage that was published in the journal "Hepatology." Several lines of evidence indicate that patients with cirrhosis presenting with gastrointestinal bleeding have a higher risk of developing bacterial infection and this in turn may be associated with early rebleeding. Short term antibiotic prophytaxis should be considered standard care in cirrhotic patients with variceal bleeding. Nevertheless, yet again a therapy with confirmed efficacy in reducing rebleeding in patients with bleeding varices has failed to show an effect on survival.


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