Immunization Against Alzheimer's Disease and Other Neurodegenerative Disorders (Book)
- How trinucleotide repeats may function. Jennings, Charles // Nature;11/9/1995, Vol. 378 Issue 6553, p127
Presents a summary of findings of two studies on hereditary neurodegenerative diseases. Expansions of the trinucleotide CAG; Interaction between the mutated proteins and others specific to the brain; Prospect of a biochemical assay for the pathogenetic process.
- Drug discovery approaches for the treatment of neurodegenerative diseases. // Journal of Medical Genetics;Sep2006 Supplement, Vol. 43, pS36
An abstract of the article "Drug discovery approaches for the treatment of neurodegenerative diseases," by Menelas N. Pangalos is presented.
- NEUROLOGICAL SYMPOSIUM. Goldberg, Daniel J. // BioScience;Mar1985, Vol. 35 Issue 3, p191
Reviews the book 'Molecular Aspects of Neurological Disorders,' edited by Lawrence Austin and Peter L. Jeffrey.
- Memory in Neurodegenerative Disease: Biological, Cognitive, and Clinical Perspectives. Dening, Tom // British Journal of Psychiatry;Jul99, Vol. 175, p98
The article reviews the book "Memory in Neurodegenerative Disease: Biological, Cognitive, and Clinical Perspectives," edited by Alexander I. Troster.
- Role of proteases in the pathophysiology of neurodegenerative diseases (Book). Gentleman, S. // Journal of Neurology, Neurosurgery & Psychiatry;May2003, Vol. 74 Issue 5, p694
Reviews the book 'Role of Proteases in the Pathophysiology of Neurodegenerative Diseases,' edited by Abel Lajtha and Maren L. Banik.
- Corrigendum: Combating neurodegenerative disease with chemical probes and model systems. Narayan, Priyanka; Ehsani, Sepehr; Lindquist, Susan // Nature Chemical Biology;Feb2015, Vol. 11 Issue 2, p172
A correction to the article "Combating neurodegenerative disease with chemical probes and model systems" that was published online on October 17, 2014 issue is presented.
- Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis. Collard, Jean-Francois; Cote, Francine // Nature;5/4/1995, Vol. 375 Issue 6526, p61
Examines axonal transport of newly synthesized proteins in mice that overexpress the human NF-H gene, to investigate how disorganized neurofilaments might cause neurodegeneration. Results of ultrastructural analysis; Conclusion.
- ARE THE EXPERIMENTAL MODELS USED TO STUDY NEURODEGENERATION SUITABLE TO COLLECT INFORMATION TO DEVELOP NEW THERAPY ACTIONS IN NEURODEGENERATIVE DISEASES? Guillemin, Gilles // Neurotoxicity Research;2008, Vol. 13 Issue 2, p149
Over the last two decades, understanding of the molecular mechanisms involved in neurodegenerative diseases has significantly increased. This is particularly true for Alzheimer's disease (AD) and motor neuron diseases such as amyotrophic lateral sclerosis (ALS). We aim to discuss here the...
- Î±-Synuclein is phosphorylated in synucleinopathy lesions. Fujiwara, Hideo; Hasegawa, Masato; Dohmae, Naoshi; Kawashima, Akiko; Masliah, Eliezer; Goldberg, Matthew S.; Shen, Jie; Takio, Koji; Iwatsubo, Takeshi // Nature Cell Biology;Feb2002, Vol. 4 Issue 2, p160
The deposition of the abundant presynaptic brain protein Î±-synuclein as fibrillary aggregates in neurons or glial cells is a hallmark lesion in a subset of neurodegenerative disorders. These disorders include Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system...