TITLE

Chapter 16: Quantitative and Qualitative Platelet Disorders

AUTHOR(S)
Ciesla, Betty
PUB. DATE
January 2007
SOURCE
Hematology in Practice;2007, p245
SOURCE TYPE
Book
DOC. TYPE
Book Chapter
ABSTRACT
Chapter 16 of the book "Hematology in Practice" is presented. It focuses on quantitative and qualitative platelet disorders. It discusses the pathophysiology of various quantitative platelet disorders such as thrombocytopenia related to decreased production and thrombocytopenia related to the immune effect of specific drugs or antibody formation. Also included are treatment options for von Willebrand's disease, Bernard Soulier Syndrome, and other qualitative platelet disorders, along with vascular disorders that can lead to platelet dysfunction.
ACCESSION #
28628523

 

Related Articles

  • High-dose dexamethasone as a first- and second-line treatment of idiopathic thrombocytopenic purpura in adults. Borst, F.; Keuning, J.J.; van Hulsteijn, H.; Sinnige, H.; Vreugdenhil, G. // Annals of Hematology;Dec2004, Vol. 83 Issue 12, p764 

    The current first-line choice of treatment of idiopathic thrombocytopenic purpura (ITP) in adults, prednisone, is effective but has many side effects. Furthermore, reduction of the dose leads to a relapse of ITP in a majority of cases. Courses of high-dose dexamethasone (HD) aim to avoid these...

  • Severe Dengue Is Associated with Consumption of von Willebrand Factor and Its Cleaving Enzyme ADAMTS-13. Djamiatun, Kis; Van der Ven, Andre J. A. M.; de Groot, Philip G.; Faradz, Sultana M. H.; Hapsari, D.; Dolmans, Wil M. V.; Sebastian, Silvie; Fijnheer, Rob; de Mast, Quirijn // PLoS Neglected Tropical Diseases;May2012, Vol. 6 Issue 5, p1 

    Background: Thrombocytopenia, bleeding and plasma leakage are cardinal features of severe dengue. Endothelial cell activation with exocytosis of Weibel-Palade bodies (WPBs) may play an etiological role in this condition. Methods and Principal Findings: In a cohort of 73 Indonesian children with...

  • Clinical practice. Ommen, C.; Peters, Marjolein // European Journal of Pediatrics;Jan2012, Vol. 171 Issue 1, p1 

    Mucocutaneous bleeding is common in childhood and may be the result of primary hemostatic disorders such as vascular abnormalities, von Willebrand disease, thrombocytopenia, and platelet dysfunction. A detailed bleeding history and physical examination are essential to distinguish between normal...

  • Elevated platelet count, leukocytosis correlated with lower risk of thrombosis. Moake, Joel // Hem/Onc Today;12/25/2008, Vol. 9 Issue 23, p46 

    The article focuses on a study which found that elevated platelet counts along with other risk factors were correlated with a lower risk of thrombosis among patients with essential thrombocythemia. The study evaluated a cohort of 1,063 patients with essential thrombocythemia in order to...

  • Willebrand factor in von Willebrand's disease.  // British Medical Journal;11/15/1975, Vol. 4 Issue 5993, p384 

    Evaluates the risk factors of von Willebrand's diseases. Complication of disease due to prolonged bleeding and reduced plasma clotting factors; Identification of reduced antigenic factors VIII and diminished glass-induced adhesion and ristocetin induced aggregation of plasma; Classification of...

  • Treatment of Immune Thrombocytopenic Purpura in Children: Current Concepts. Shad, Aziza T.; Gonzalez, Corina E.; Sandler, S. G // Pediatric Drugs;2005, Vol. 7 Issue 5, p325 

    Treatment of immune thrombocytopenic purpura (ITP), the most common bleeding disorder of childhood, is a controversial subject for most practitioners. Diagnosis and management of ITP has historically been based primarily on expert opinion rather than on evidence. Due to a paucity of carefully...

  • Heparin.  // Reactions Weekly;11/15/2008, Issue 1228, p20 

    The article describes the case of a 49-year-old man who was diagnosed with heparin-induced thrombocytopenia (HIT) antibodies. The patient tested positive for the said condition while undergoing treatment with intravenous (IV) heparin. He was subjected to thrombectomy and was administered with...

  • Spontaneous bleeding in a mill worker. Tetreault, Scott A. // Cortlandt Forum;10/25/99, Vol. 12 Issue 10, p168 

    Focuses on the spontaneous bleeding experienced by a mill worker with Von Willebrand's disease in the United States. Cause of the bleeding disorder acquired by the patient; Medical causes of bleeding; Symptoms for clotting factor abnormalities; Mechanisms resulting to thrombocytopenia; Use of...

  • Heparin-induced Thrombocytopenia and Thrombosis Syndrome. Wallis, Diane E.; Lewis, Bruce E.; Messmore, Harry; Wehrmacher, William H. // Clinical & Applied Thrombosis/Hemostasis;Jul1998, Vol. 4 Issue 3, p160 

    Discusses heparin-induced thrombocytopenia (HIT) and HIT with thrombosis syndrome. Pathophysiology and clinical expression; Diagnosis; Treatment.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics