The effects of Vaccinium arctostaphylos on lipid profile in mild hyperlipidemia patients- a randomized clinical trial

Hakimi, M.; Soltani, R.; Keshvari, M.; Asgari, S.; Sarrafzadegan, N.
December 2014
Journal of Shahrekord University of Medical Sciences;Dec2014/Jan2015, Vol. 16 Issue 5, p92
Academic Journal
Background and aims: Hyperlipidemia, or increased of blood fat, is known as an independent and curable risk factor in cardiovascular disease. The aim of this study was to examine the effects of Vaccinium arctostaphylos on lipid profile levels in patients with hyperlipidemia. Methods: in this randomized clinical trial, double-blind study, 50 patients in the age ranges between 14-76 years old with low hyperlipidemia participated in the study. Patients were randomly divided into two control and case group. Patients in case group received 2 capsule of V. arctostaphylos daily and control group received placebo for 1 month. At the beginning and in the end of the study, serum levels of triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL) and decreasing in the of level of high density lipoprotein (HDL) were compared. Results: There were no significant difference in the characteristics of the subjects (age, TC, LDL, HDL, TG, and BMI), between the two groups at baseline. The mean of changes in the group receiving V. arctostaphylos with the control group regarding this factors (TC: 226.48±32.09 vs 192.04±28.81, LDL-C: 132.80±23.76 vs 121.36±27.46, TG: 226.20±96.99 vs 156.56±46.76) for one month, showed a significantly decrease (P<0.05), but it showed no significant differences in BMI and HDL-C factors (p>0.05). Conclusion: V. arctostaphylos consumption during a month led to decreasing in lipid profile in hyperlipidemia patients. So, this plant could be effective in preventing the prevalence of cardiovascular diseases.


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