Infection remains a leading cause of neonatal mortality among infants delivered at a tertiary hospital in Karachi, Pakistan

Mustufa, Muhammad Ayaz; Korejo, Razia; Shahid, Anjum; Nasim, Sadia
November 2014
Journal of Infection in Developing Countries;Nov2014, Vol. 8 Issue 11, p1470
Academic Journal
Introduction: The current cohort study was conducted to determine the frequency and compare the mortality rate with associated characteristics among low birth weight and normal birth weight infants during the neonatal period at a tertiary healthcare facility, Karachi. Methodology: Close-ended structured questionnaires were used to collect information from the parents of 500 registered neonates at the time of birth. Follow-ups by phone on the 28th day of life were done to determine the mortality among low birth weight and normal birth weight babies during the neonatal period. Results: The neonatal mortality rate ranged from as low as 2.4% in the normal birth weight and 16.4% in the low birth weight categories to as high as 96% in the very low birth weight category. Respiratory distress syndrome (24.2%) and sepsis (18.2%) were reported as the leading causes of neonatal deaths. The babies' lengths of stay ranged from 2 to 24 hours, and around 90% of neonatal deaths were reported in the first seven days of life. More than 6% of neonates died at home, and 7.6% of the deceased babies did not visit any healthcare facility or doctor before their death. In the 12-15 hours before their deaths, 13.6% of the deceased babies had been unattended. Around 90% of the deceased babies were referred from a doctor or healthcare facility. Conclusions: The present estimates of neonatal mortality are very high among low birth weight and very low birth weight categories. Infectious diseases, including respiratory distress syndrome (24.2%) and sepsis (18.2%), were leading causes of neonatal deaths.


Related Articles

  • Mid-arm and chest circumference at birth as predictors of low birth weight and neonatal mortality in the community. Bhargava, S.K.; Ramji, S.; Kumar, Arun; Mohan, Man; Marwah, Jasbir; Sachdev, H.P.S. // British Medical Journal (Clinical Research Edition);12/7/1985, Vol. 291 Issue 6509, p1617 

    Evaluates the measurement of mid-arm and chest circumference as predictors of low birth weight and neonatal mortality in India. Correlation between anthropometric variables and birth weight; Provision of primary health care; Reliability of birth weight as indicator of the later outcome of a...

  • Rural-urban differences of neonatal mortality in a poorly developed province of China. Bin Yi; Li Wu; Hong Liu; Weimin Fang; Yang Hu; Youjie Wang // BMC Public Health;2011, Vol. 11 Issue 1, p477 

    Background: The influence of rural-urban disparities in children's health on neonatal death in disadvantaged areas of China is poorly understood. In this study of rural and urban populations in Gansu province, a disadvantaged province of China, we describe the characteristics and mortality of...

  • Perinatal infections impaired development of at-risk infants.  // Infectious Diseases in Children;Aug2013, Vol. 26 Issue 8, p9 

    The article reports on a study published in "JAMA Pediatrics," which found that mental and motor development of very preterm and very low birth-weight children are negatively affected by perinatal infections.

  • Low birth weight and its relation to unwanted pregnancies; A cohort study. Hosseini, M.; Ghavami, B.; Salimzadeh, H.; Eftekhar, H. // Journal of School of Public Health & Institute of Public Health ;2009, Vol. 7 Issue 1, p11 

    Background and Aim: Unwanted pregnancy is a widespread problem globally and in Iran, which can lead to low birth weight (LBW)-one of the most important causes of mortality in newborns. This study was conducted to assess the risk factors among women with unwanted pregnancies leading to delivery...

  • Total serum bilirubin levels during the first 2 days of life and subsequent neonatal morbidity in very low birth weight infants: a retrospective review. Zhu, Jiajun; Xu, Yanping; Zhang, Guolian; Bao, Yingying; Wu, Mingyuan; Du, Lizhong // European Journal of Pediatrics;Apr2012, Vol. 171 Issue 4, p669 

    To determine the relationship between total serum bilirubin (TSB) during the first 2 days of life and subsequent neonatal morbidity in very low birth weight (VLBW, less than 1500 g) infants. We performed a prospective study of 582 VLBW infants born between July 1, 2005 and December 31, 2009. TSB...

  • Effect of Instrument Precision on Estimation of Low Birth Weight Prevalence. Mullany, Luke C; Darmstadt, Gary L; Katz, Joanne; Khatry, Subarna K; Tielsch, James M // Journal of Perinatology;Jan2005, Vol. 25 Issue 1, p11 

    OBJECTIVE:: Reductions in prevalence of low birth weight (LBW) are likely to be achieved only through small increments, amplifying the importance of precision of measurement. This study compared two instruments for measuring birth weight to investigate the effect of instrument precision on...

  • Reducing Neonatal Mortality in Jhagadia Block, Gujarat: We Need to go Beyond Promoting Hospital Deliveries. Kutty, V.Raman; Shah, Pankaj; Modi, Dhiren; Shah, Shobha; Ramanathan, Mala; Archana, A. R. // Journal of Tropical Pediatrics;Feb2013, Vol. 59 Issue 1, p49 

    Background and Methods: We examined data from a cohort of births that occurred in the period 2004–08 in the SEWA-Rural project area, covering a population of ∼175000, in Gujarat, India, to assess the trends and risk factors for neonatal mortality.Results: In this population living in...

  • Early-onset sepsis increased mortality, morbidity risk. Cox, Amber; Shafer, Emily // Infectious Disease News;Dec2013, Vol. 26 Issue 12, p12 

    The article reports on the increase in risk for mortality and major morbidities among very low birth weight infants with early-onset sepsis, according to a study by A. Mularoni and other researchers published in "The Pediatric Infectious Disease Journal" as of December 2013.

  • Maternal malaria prevention reduced neonatal mortality, low birth weight.  // Infectious Disease News;Dec2012, Vol. 25 Issue 12, p39 

    The article discusses a study on the effectiveness of preventing malaria during pregnancy in reducing neonatal mortality and low birth weight.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics