TITLE

Conditioned pain modulation in temporomandibular disorders (TMD) pain patients

AUTHOR(S)
Oono, Yuka; Wang, Kelun; Baad-Hansen, Lene; Futarmal, Simple; Kohase, Hikaru; Svensson, Peter; Arendt-Nielsen, Lars
PUB. DATE
October 2014
SOURCE
Experimental Brain Research;Oct2014, Vol. 232 Issue 10, p3111
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The aims were to investigate (1) if temporomandibular disorders (TMD) patients with temporomandibular joint (TMJ) pain had different conditioned pain modulation (CPM) compared with healthy subjects and, (2) if clinical pain characteristics influenced CPM. Sixteen TMD pain patients and 16 age-matched healthy subjects were participated. A mechanical conditioning stimulus (CS) was applied to pericranial muscles provoking a pain intensity of 5/10 on a visual analogue scale. Pressure pain thresholds (PPT) and pressure pain tolerance thresholds (PPTol) were assessed at masseter, forearm and painful TMJ (only PPT) before, during, and 20 min after CS. Data were analyzed with ANOVAs. The correlations between CPM effect and ratings of TMD pain intensity on a numerical rating scale (NRS) or the pain duration were calculated (correlation coefficient; R). The relative PPT and PPTol increases (mean for the three assessment sites) during CS were significantly higher than baseline in healthy subjects (43.0 ± 3.6, 33.0 ± 4.0 %; P < 0.001, P < 0.001) but not in the TMD pain patients (4.9 ± 2.7, −1.4 ± 4.1 %; P = 0.492, P = 1.000) with significant differences between groups ( P < 0.001). In the patients, the relative PPT changes during CS were not significantly higher than baseline at TMJ (5.3 ± 3.8 %, P = 0.981) and masseter (−2.8 ± 4.8 %, P = 1.000) but significantly higher at forearm (12.3 ± 4.7 %, P = 0.039). No correlation was detected between TMD pain intensity and CPM effect ( R = −0.261; P = 0.337) or between pain duration and CPM effect ( R = −0.423; P = 0.103) at painful TMJ. These findings indicate that CPM is impaired in TMD pain patients especially at sites with chronic pain but not at pain-free sites and that the clinical pain characteristics do not influence CPM.
ACCESSION #
98371939

 

Related Articles

  • Generic Pain Intensity Scores Are Affected by Painful Comorbidity. Türp, Jens C.; Kowalski, Charles J.; Stohler, Christian S. // Journal of Orofacial Pain;Winter2000, Vol. 14 Issue 1, p47 

    Aims: To determine the degree to which the generic pain intensity rating (ie, overall and without reference to a particular body site) of facial pain patients being seen in a specialty setting for facial pain is influenced by painful comorbidity in body parts other than the face. Methods: In...

  • Trigeminal neuralgia: treat but do not prolong.  // British Medical Journal (Clinical Research Edition);6/6/1981, Vol. 282 Issue 6279, p1820 

    Examines the management of trigeminal neuralgia in Great Britain. Occurrence of paroxysmal, lancinating pains, provoking stimuli, trigger points and direction of spread; Development of chronic burning facial pain; Details on dental malocclusion and temporomandibular dysfunction.

  • VARIABILITY OF THE PAIN THRESHOLD IN MAN. SCHAMP, J. R.; SCHAMP, H. M. // Journal of Dental Research;Apr1946, Vol. 25 Issue 2, p101 

    The article presents the results of a study which attempted to find a reliable metric for pain in humans. An overview of related previous research is provided, along with details of the experimental protocol. It was found that the methods used produced results which varied greatly between...

  • Changes in Pressure-Pain Thresholds of the Jaw Muscles During a Natural Stressful Condition in a Group of Symptom-Free Subjects. Michelotti, Ambra; Farella, Mauro; Tedesco, Antonietta; Cimino, Roberta; Martina, Roberto // Journal of Orofacial Pain;Fall2000, Vol. 14 Issue 4, p279 

    Aims: To investigate the effects of a natural emotional stressor on pressure-pain thresholds (PETs) of the masticatory muscles of symptom-free subjects. Methods: Sixteen healthy dental students were selected before they undertook an academic examination. Sixteen gender-matched students who were...

  • WHAT'S BEHIND YOUR JAW PAIN. Greenberger, Phyllis // Shape;Apr2010, Vol. 29 Issue 8, p94 

    The article discusses temporomandibular disorders in women.

  • Pressure Pain Threshold of the Posterior Aspect of the Temporomandibular Joint Measured with a Semi-Spherical Probe. Nordahl, Silvi; Kopp, Sigvard // Journal of Orofacial Pain;Spring2003, Vol. 17 Issue 2, p145 

    Aims: To develop and test a probe for measurement of the pressure pain threshold (PPT) over the posterior aspect of the temporomandibular joint (TMJ) in healthy individuals, including determination of PPT levels, reliability, and the smallest detectable difference (SDD) between measurements....

  • Trigeminal neuralgia and chiropractic care: a case report. Rodine, Robert J.; Aker, Peter // Journal of the Canadian Chiropractic Association;Sep2010, Vol. 54 Issue 3, p177 

    The following case describes a 68 year-old woman with a 7½ year history of worsening head and neck pain diagnosed as trigeminal neuralgia following surgical resection of a brain tumor. After years of unsuccessful management with medication and physical therapies, a therapeutic trial of...

  • A Randomized Clinical Trial of a Tailored Comprehensive Care Treatment Program for Temporomandibular Disorders. Dworkin, Samuel F.; Turner, Judith A.; Mancl, Lloyd; Wilson, Leanne; Massoth, Donna; Huggins, Kimberly H.; LeResche, Linda; Truelove, Edmond // Journal of Orofacial Pain;Fall2002, Vol. 16 Issue 4, p259 

    Aims: To test the usefulness of tailoring cognitive-behavioral therapy (CBT) for patients with temporomandibular disorders (TMD) who demonstrated poor psychosocial adaptation to their TMD condition, independent of physical diagnosis. Methods: A randomized clinical trial compared a 6-session CBT...

  • A Comparison Between Masticatory Muscle Pain Patients and Intracapsular Pain Patients on Behavioral and Psychosocial Domains. Lindroth, John E.; Schmidt, John E.; Carlson, Charles R. // Journal of Orofacial Pain;Fall2002, Vol. 16 Issue 4, p277 

    Aims: To identify differences between 2 groups of patients with temporomandibular disorders (TMD), those with masticatory muscle pain (MMP) versus intracapsular pain (ICP), and to compare these differences on behavioral and psychosocial domains. Methods: There were 435 patients in the MMP group...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics