TITLE

MODERATE PERSISTENT ASTHMA IN CHILDREN; COMPARISON OF INHALED BECLOMETHASONE WITH ORAL MONTELUKAST IN THE MANAGEMENT

AUTHOR(S)
Saqib, Aqdas; Ismail, Saqib; Yasir, Saadia
PUB. DATE
October 2014
SOURCE
Professional Medical Journal;2014, Vol. 21 Issue 4, p704
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective: The objective of this study is to compare the effects of inhaled beclomethasone with oral montelukast in long term management of moderate persistent asthma in children. Design: Quasi experimental study. Period: 6 months, from July 20,2007 to January 20, 2008. Settings: Out patient paediatric department at Fauji Foundation hospital, Rawalpindi. Material and Methods: 80 children between 5-12yrs of age presenting with moderate persistent asthma, divided in two groups of 40 each. Group A treated with beclomethasone inhaler while Group B was started on oral montelukast. Drugs effect was recorded on a 2 wkly proforma for 8 weeks. Results: There were 54(67.5%) male and 26(33%) female. Most common triggering factor seen in 54(67.5%) patients was recent history of respiratory tract infection, exposure to carpet dust in 43(53.75%), cigarette smoke in 42(52.5%),recent psychological stress in 28(35%) , pollen allergy in 26 (32.5%) , pets exposure in 8 (10%) and to mite was noticed in 5(6.25%) children. Marked improvement was observed in day time cough in group A with 10(25%) patients being free of cough with inhaler, while 20(50%) showed mild intermittent symptoms. 1(2.5%) showed mild persistent symptoms. In Group B 3(7.5%) patients were symptom free, 23(57.5%)with mild intermittent and 4(10%) with mild persistant symptoms while 6(15%) continued to have moderate persistent symptoms. P value was 0.01. Regarding day time breathlessness, P value was significant of 0.258. Similarly marked improvement was observed in night symptoms of breathlessness, cough and sleeplessness in both groups. P value was less than 0.05 in majority of the variables showing statistically significant improvement with inhaled beclomethasone than with oral montelukast. Conclusions: Inhaled beclomethasone is superior to oral montelukast in controlling chronic symptoms of childhood asthma.
ACCESSION #
98177675

 

Related Articles

  • One-Year Trial on Safety and Normal Linear Growth with Flunisolide HFA in Children with Asthma. Gillman, Sherwin A.; Anolik, Robert; Schenkel, Eric; Newman, Kenneth // Clinical Pediatrics;Jun2002, Vol. 41 Issue 5, p333 

    Presents information on a study that compared the year-long safety of flunisolide hydrofluoroalkane with that of chlorofluorocarbon beclomethasone dipropionate and cromolyn sodium in children with asthma. Effects of the drugs on linear growth and growth velocity; Safety parameters; Results and...

  • Beclomethasone vs. theophylline for asthma.  // American Family Physician;1/1/1994, Vol. 49 Issue 1, p213 

    Compares the effectiveness of aerosol beclomethasone and sustained release oral theophylline in the treatment of asthmatic children as reported by Tinkelman and associates in the July 1993 issue of `Pediatrics.' Side effects; Reliance on supplemental medication; Growth velocity suppression.

  • Efekti topijske primene beklometazon dipropionata na simptome hroničnog rinitisa. Ursulovic, Dejan; Janoševic, Ljiljana; Janoševic, Slobodanka; Dukic, Vojko // Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journ;Jan/Feb2003, Vol. 60 Issue 1, p29 

    The aim of this study was to evaluate the effect of topical administration of corticosteroid beclomethasone dipropionate on common nasal symptoms in moderate allergic and non-allergic hyperreactive eosinophilic rhinitis, and in allergic and non-allergic hyperreactive eosinophilic rhinitis...

  • In children and adolescents with mild persistent asthma, daily beclomethasone reduces treatment failure compared with rescue beclomethasone plus albuterol. Kovesi, Tom // Evidence Based Medicine;Dec2011, Vol. 16 Issue 6, p183 

    The article presents a study that deals with use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma. The study evaluates the efficacy of this approach in children potentially ready to be weaned off inhaled corticosteroids. It investigates the efficacy of...

  • Choosing Therapy for Childhood Asthma. Holgate, Stephen T.; Frew, Anthony J. // New England Journal of Medicine;12/04/97, Vol. 337 Issue 23, p1690 

    Editorial. Focuses on choosing a therapy for childhood asthma. The availability of inhaled corticosteroids, cromolyn sodium or nedocromil sodium, beclomethasone dipropionate and salmeterol; Other options, such as environmental interventions; Reference to work by Simons et al in same issue.

  • Child health. Macdonald, Mary // Pulse;4/27/2011, Vol. 71 Issue 15, p20 

    The article reports developments in child health in Great Britain. It explores the new World Health Organization (WHO) child growth charts launched in 2009. It offers information on the new guidelines published by the National Institute for Health and Clinical Excellence (NICE). It relates a...

  • A Comparison of the Treatment of Severe Injuries Between the Former East and West German States. Mand, Carsten; Müller, Thorben; Lefering, Rolf; Ruchholtz, Steffen; Kühne, Christian A. // Deutsches Aerzteblatt International;3/21/2013, Vol. 110 Issue 12, p203 

    Background: The annual number of persons killed in road-traffic accidents in Germany declined by 36% from 2001 to 2008, yet official traffic statistics still reveal a marked difference in fatalities between the federal states of the for - mer East and West Germany twenty years after German...

  • Effectiveness of Multisystemic Therapy for Minority Youth: Outcomes Over 8 Years in Los Angeles County. Fain, Terry; Greathouse, Sarah Michel; Turner, Susan F.; Weinberg, H. Dawn // Journal of Juvenile Justice;Spring2014, Vol. 3 Issue 2, p24 

    Previous research on Multisystemic Therapy© (MST), an intensive family and community-based treatment for juvenile offenders between 12 and 18 years of age, has been based on small samples that have included very few Hispanic youth. This paper examines juvenile justice outcomes and costs for...

  • Speak Out. Blick, Shawn D.; Gomez, Michael S.; McKimmy, Roger M.; Sobie, Jon // Urology Times;May2011, Vol. 39 Issue 5, p58 

    The article presents views of several physicians related to the effectiveness for prostate cancer treatment modalities such as Michael S. Gomez, Roger M. McKimmy, and Shawn D. Blick.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics