TITLE

Oral Fluid Based Biomarkers in Periodontal Disease: Part 1. Saliva

AUTHOR(S)
AlMoharib, Hani S.; AlMubarak, Abdulrahman; AlRowis, Raed; Geevarghese, Amrita; Preethanath, R. S.; Anil, Sukumaran
PUB. DATE
July 2014
SOURCE
Journal of International Oral Health;2014, Vol. 6 Issue 4, p95
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Traditional clinical measurements such as probing pocket depth, bleeding on probing, clinical attachment loss; plaque index and radiographs used for periodontal diagnosis are often of limited usefulness as they are indicators of previous periodontal disease rather than present disease activity. A literature search was carried out to find out all the available tests that indicate periodontal disease markers in saliva. All major databases were searched to compile the information on published reports between 1999 and 2014. The list of biomarkers available to date is compiled and presented in a table format. Each biomarker is discussed separately based on the available evidence. Based on the evidence, it can be concluded that several sensitive salivary indicators of periodontitis are available to detect the presence, severity and response to treatment. Further studies are warranted to analyze the sensitivity and reliability of these indicators that might help in developing non-invasive tests that could help in the diagnosis of periodontal disease.
ACCESSION #
97913423

 

Related Articles

  • Activation of Complement by Treponema denticola. SCHENKEIN, H. A.; BERRY, C. R. // Journal of Dental Research;Feb1991, Vol. 70 Issue 2, p107 

    Oral spirochetes have been shown to be associated with periodontal diseases and are present in increased numbers in lesions of greater severity. In this study, the interaction of Treponema denticola with human complement, a major antibacterial defense system, was examined. For each of two...

  • Self-Inflicted Gingival Trauma in a 13-Year-Old Girl: What are the Psychosocial Issues that May Underlie this Behaviour? Chapple, Iain L. C.; Malik, Khalid; Freeman, Ruth // Periodontal Practice Today;2005, Vol. 2 Issue 3, p219 

    A 13-year-old girl was referred by her orthodontist for pre-orthodontic management of her gingival condition that, despite the implementation of appropriate and targeted oral hygiene measures, had not improved and was inconsistent with her level of plaque control. We shall call her by a pseudo...

  • Dry Mouth affects Millions and can damage teeth.  // Oral Health (0974-3960);Oct2016, Vol. 10 Issue 10, p31 

    The article focuses on dry mouth disease in adults in United States and mentions topics such as oral health, saliva and dental plaque.

  • Oral Cavity Evaluation and Dental Chart Registration of Coati (Nasua nasua) in Captivity. Freitas, Elisângela R.; Rahal, Sheila C.; Teixeira, Carlos R.; Teixeira, Rodrigo H. F.; Mendes, Guilherme M.; Gioso, Marco A. // Journal of Veterinary Dentistry;Jun2008, Vol. 25 Issue 2, p110 

    The aims of this study were to develop a dental chart, evaluate any oral cavity disease, develop gypsum models of the dental arches, and to register the occlusions found in coatis (Nasua nasua) in captivity. Formulation of the dental chart was assisted by intraoral radiographs from the head of...

  • Plaque Accumulation in Guinea Pigs at Reduced Saliva Flow With and Without Sucrose Administration. PEYSER, Y. M.; BRAYER, L.; PITAR, A.; GEDALIA, I. // Journal of Dental Research;Oct1977, Vol. 56 Issue 10, p1172 

    The article discusses a study that looked at the amount of dental plaque on the teeth of guinea pigs with low levels of saliva. Differences that were experienced regarding the dental plaque on the teeth of the guinea pigs that were given sucrose are discussed. The potential impact that the...

  • Local Effect of Therapeutic Agents on Plaque Composition. Tatevossian, A.; Jenkins, G.N.; Edgar, W.M. // Journal of Dental Research;Jun1975 Supplement, Vol. 54 Issue 2, pB34 

    The article describes a study which assessed the local effect of therapeutic phosphate agents on the composition of dental plaque. The findings of the study showed that the plaque phosphate content did not increase with sugar having phosphate supplement of 0.37% P. This is because the phosphate...

  • utilization of a biochemical kit for detection of C-reactive protein (CRP) in the saliva of periodontal disease individuals. Baroni, Anaila; Souza, Juliana Marchioro; Torres, Maria Fernanda; Tomazinho, Paulo Henrique; Brancher, João Armando // RSBO: Revista Sul-Brasileira de Odontologia;jul2011, Vol. 8 Issue 3, p282 

    Introduction: Periodontal disease (PD) is a chronic inflammatory process that occurs in response to infection from bacteria in dental plaque. PD affects and destroys the periodontal tissues causing teeth loss. It is also associated to systemic diseases. C-reactive protein (CRP) is a protein...

  • Dental Calculus Formation Rate in a Submarine Environment. PIEBENGA, L. W.; SHILLER, W. R. // Journal of Dental Research;Jul1968, Vol. 47 Issue 4, p613 

    Calculus formation rates were evaluated in men living in closed, elevated CO2 environments of submarines. These rates were compared with values obtained prior to submarine patrol duty. The standardized Mylar foil technic was employed to collect calculus from the lower anterior teeth. Analysis...

  • Inflammatory Immune Responses by Water-insoluble α-glucans. Okamoto, S.; Terao, Y.; Kaminishi, H.; Hamada, S.; Kawabata, S. // Journal of Dental Research;Mar2007, Vol. 86 Issue 3, p242 

    Water-insoluble α-glucans are synthesized from sucrose by glucosyltransferase-I of mutans streptococci and play an important role in the development of dental plaque. Several types of β- glucans in fungal cell wall components and watersoluble α-glucans from Streptococcus mutans are...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics