TITLE

ZEB Family in Epithelial-mesenchymal Transition of Epithelial Ovarian Cancer

AUTHOR(S)
LI Yi-ying; JIANG Hua
PUB. DATE
February 2014
SOURCE
Journal of International Obstetrics & Gynecology;Feb2014, Vol. 41 Issue 1, p47
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Epithelial ovarian cancer (EOC) is one of the most malignant tumor in women, which is inclined to get invasion and metastasis. Epithelial--mesenchymal transition (EMT) is an important phenomenon in tumor progression. It involves many signal transduction pathways and complex molecular mechanisms. Zinc finger E-box-binding protein (ZEB),an essential transcription factor during EMT, can inhibit the expression of E-cadherin and polar protein, and thus promote the EMT process. Researches of ZEB and EMT in EOC will provide effective target to block the metastasis of EOC in the future.
ACCESSION #
97776490

 

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