Prolonged Perilesional Edema after Treatment of Parenchymal Neurocysticercosis: Methotrexate as a Corticosteroid-Sparing Agent

Keiser, Paul B.; Nash, Theodore E.
May 2003
Clinical Infectious Diseases;5/15/2003, Vol. 36 Issue 10, pe122
Academic Journal
Treatment of neurocysticercosis with larvicidal agents is commonly complicated by seizures and transient neurologic deficits as a result of the host immune response to dying cysts. We report a case in which treatment with high-dose praziquantel resulted in prolonged perilesional edema requiring use of corticosteroids and corticosteroid-sparing agents for >1 year, suggesting a role for methotrexate in the management of this condition.


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