Association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in a Japanese population
- Polymorphisms in SELE Gene and Risk of Coal Workers' Pneumoconiosis in Chinese: A Case-Control Study. Wang, Ting; Ji, Xiaoming; Luo, Chen; Fan, Jingjing; Hou, Zhiguo; Chen, Minjuan; Han, Ruhui; Ni, Chunhui // PLoS ONE;Sep2013, Vol. 8 Issue 9, p1
Background: Coal workers' pneumoconiosis (CWP) is characterized by chronic pulmonary inflammation and fibrotic nodular lesions that usually lead to progressive fibrosis. Inflammation is the first step in the development of CWP. E-selectin, an adhesion molecule, is involved in the development of...
- Association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in different populations. Papa, A.; Danese, S.; Armuzzi, A.; Gaetani, E.; Flex, A.; Pola, P.; Gasbarrini, A. // Gut;Aug2003, Vol. 52 Issue 8, p1227
Presents a letter to the editor published in the August 2003 issue of 'Gut' journal about the association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in different populations.
- Authors' reply. Sugimura, K.; Matsuzawa, J. // Gut;Aug2003, Vol. 52 Issue 8, p1228
Presents a letter to the editor published in the August 2003 issue of 'Gut' journal responding to the author's article about the association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in different populations.
- A functional analysis of a natural variant of intercellular adhesion molecule-1 (ICAM-1[sup Kilifi]). Craig, Alister // Human Molecular Genetics;Mar2000, Vol. 9 Issue 4, p525
Reports on functional assays using both forms of intercellular adhesion molecule-1 (ICAM-1) as soluble Fc chimeric fusion proteins to understand the mechanism by which polymorphisms might be maintained despite counter-selection by malaria. Involvement of ICAM-1 in a range of interactions both...
- Cytokine (TNFÎ±, LTÎ± and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: differential effects on production and allele frequencies. Koss, K; Satsangi, J; Fanning, G C; Welsh, K I; Jewell, D P // Genes & Immunity;Feb2000, Vol. 1 Issue 3, p185
The influence of biallelic polymorphisms in the tumour necrosis factor-alpha (TNFÎ±), lymphotoxin-alpha (LTÎ±) and interleukin-10 (IL-10) genes on stimulated TNFÎ± and IL-10 production was studied in ulcerative colitis (UC) patients, Crohn's disease (CD) patients and in healthy controls. A...
- Investigation of the ICAM-1 G241A and A469G gene polymorphisms in schizophrenia. Riedel, M; Kronig, H; Schwarz, M J; Engel, R R; Sikorski, C; Kuhn, K-U; Behrens, S; Moller, H-J; Ackenheil, M; Muller, N // Molecular Psychiatry;2003, Vol. 8 Issue 3, p257
Molecular Psychiatry (2003) 8, 257-258. doi:10.1038/sj.mp.4001320
- Homocysteine Triggers Mucosal Microvascular Activation in Inflammatory Bowel Disease. Danese, Silvio; Sgambato, Alessandro; Papa, Alfredo; Scaldaferri, Franco; Pola, Roberto; Sans, Miquel; Lovecchio, Maria; Gasbarrini, Giovanni; Cittadini, Achille; Gasbarrini, Antonio // American Journal of Gastroenterology;Apr2005, Vol. 100 Issue 4, p886
OBJECTIVES: Increased homocysteine contributes to the pathophysiology of several chronic inflammatory diseases. Whether homocysteine could participate in mucosal inflammation in inflammatory bowel disease (IBD) has not been explored yet. Our aims were to study the levels of plasma and mucosal...
- Mucosal Gene Expression of Cell Adhesion Molecules, Chemokines, and Chemokine Receptors in Patients With Inflammatory Bowel Disease Before and After Infliximab Treatment. Arijs, Ingrid; De Hertogh, Gert; Machiels, Kathleen; Van Steen, Kristel; Lemaire, Katleen; Schraenen, Anica; Van Lommel, Leentje; Quintens, Roel; Van Assche, Gert; Vermeire, Séverine; Schuit, Frans; Rutgeerts, Paul // American Journal of Gastroenterology;Apr2011, Vol. 106 Issue 4, p748
OBJECTIVES:Inflammatory bowel disease (IBD) is characterized by a continuous influx of leukocytes into the gut wall. This migration is regulated by cell adhesion molecules (CAMs), and selective antimigration therapies have been developed. This study investigated the effect of infliximab therapy...
- Rheostat regulation of integrin-mediated leukocyte adhesion. Douglas, Ivor S.; Dassopoulos, Themistocles // Journal of Clinical Investigation;Sep2007, Vol. 117 Issue 9, p2391
The homing of activated T lymphocytes to the gut in inflammatory bowel diseases is dependent on their coordinated, integrin-mediated adhesion and de-adhesion to substrates and blood vessel walls. In this issue of the JCI, Park and colleagues reveal a key modulatory role of a binding site within...