Avenin fails to induce a Th1 response in coeliac tissue following in vitro culture
- HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22. Bodd, M.; Ráki, M.; Tollefsen, S.; Fallang, L. E.; Bergseng, E.; Lundin, K. E. A.; Sollid, L. M. // Mucosal Immunology (1933-0219);Nov2010, Vol. 3 Issue 6, p594
We have analyzed the production of the effector cytokines interleukin (IL)-17, IL-21, and IL-22 in gluten-reactive CD4+ T cells of celiac disease patients, either cultured from small intestinal biopsies or isolated from peripheral blood after an oral gluten challenge. Combining intracellular...
- Standardised approach to gluten challenge in diagnosing childhood coeliac disease. Rolles, Christopher J.; McNeish, Alexander S. // British Medical Journal;5/29/1976, Vol. 1 Issue 6021, p1309
Examines the standardized approach to gluten challenge in diagnosing childhood coeliac disease. Performance of a repeat biopsy; Obtainment of a definitive proof of gluten-sensitive enteropathy; Symptoms of the disease.
- DOES ADOPTION OF BSG GUIDELINES FOR MANAGEMENT OF IRON DEFICIENCY ANAEMIA (IDA) RESULT IN AN INCREASE IN UNNECESSARY DUODENAL BIOPSIES? Ferguson, H.R.; Sommerville, J.; Murphy, P. // Gut;Apr2003 Supplement 1, Vol. 52, pA99
Introduction: The British Society of Gastroenterology guidelines for the management of IDA suggest that duodenal biopsy should be done as a routine at the time of OGD in all patients. These guidelines were adopted in our trust but there was concern that they may increase the workload of an...
- Re: M Saginur, FAM AlRefaee, DW Spady, et al. Antitissue transglutaminase antibody determination versus upper endoscopic biopsy diagnosis of paediatric celiac disease. Paediatr Child Health 2013;18(5):246-250. Jong, Geert't // Paediatrics & Child Health (1205-7088);Aug/Sep2013, Vol. 18 Issue 7, p384
A letter to the editor is presented in response to the article "Antitissue transglutaminase antibody determination versus upper endoscopic biopsy diagnosis of paediatric celiac disease" in the previous issue.
- Is intestinal biopsy always needed for diagnosis of celiac disease? Scoglio, Riccardo; Di Pasquale, Giuseppe; Pagano, Giuseppe; Lucanto, Maria Cristina; Magazzù, Giuseppe; Sferlazzas, Concetta // American Journal of Gastroenterology;Jun2003, Vol. 98 Issue 6, p1325
: ObjectiveIntestinal biopsy is required for a diagnosis of celiac disease (CD). The aim of this study was to assess diagnostic accuracy of transglutaminase antibodies (TGA) in comparison and in association with that of antiemdomysial antibodies (AEA), calculating the post-test odds of having...
- What is the best histopathological classification for celiac disease? Does it matter? A letter of comment to the review of Amado Salvador Pena; a new proposal. Villanacci, Vincenzo // Gastroenterology & Hepatology from Bed to Bench;Autumn2015, Vol. 8 Issue 4, p306
A letter to the editor is presented in response to a review by Amado Salvador Pena on issues pertaining to the histopathological classification of celiac disease.
- Mucosal Cytokine Response After Short-Term Gluten Challenge in Celiac Disease and Non-Celiac Gluten Sensitivity. Brottveit, Margit; Beitnes, Ann-Christin R; Tollefsen, Stig; Bratlie, Jorunn E; Jahnsen, Frode L; Johansen, Finn-Eirik; Sollid, Ludvig M; Lundin, Knut E A // American Journal of Gastroenterology;May2013, Vol. 108 Issue 5, p842
OBJECTIVES:In celiac disease (CD), gluten induces both adaptive and innate immune responses. Non-celiac gluten sensitivity (NCGS) is another form of gluten intolerance where the immune response is less characterized. The aim of our study was to explore and compare the early mucosal immunological...
- Celiac disease: Early diagnosis leads to the best possible outcome. Milito, Toni Marie; Muri, Matthew; Oakes, Jessica; Spivey, Jessica; Covino, Jean // JAAPA: Journal of the American Academy of Physician Assistants (;Nov2012, Vol. 25 Issue 11, p43
The article offers information on celiac disease, a chronic autoimmune disease provoked through gluten insensitivity. It is a result of inflammation which is caused due to the destruction of intestinal mucosa. It reports 4 manifestations of CD including classic, silent, atypical or latent....
- Pediatric Celiac Disease: Clinicopathologic and Genetic Aspects. Lowichik, Amy; Book, Linda // Pediatric & Developmental Pathology;Nov/Dec2003, Vol. 6 Issue 6, p470
Evaluation for celiac disease (CD), an autoimmune enteropathy triggered by grain proteins in wheat, barley, rye, and possibly oats, is a common indication for pediatric endoscopy and biopsy. Duodenal or jejunal biopsy remains key for the initial diagnosis of CD. Small intestinal pathology may be...