TITLE

RUNX 3, apoptosis 0: a new gastric tumour suppressor

AUTHOR(S)
Moss, S.F.
PUB. DATE
January 2003
SOURCE
Gut;Jan2003, Vol. 52 Issue 1, p12
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Reports on the exhibition of hyperplasias by Runx3/Pebp2alphaC null mouse gastric mucosa due to stimulated proliferation and suppressed apoptosis in epithelial cells. Resistance of cells to growth-inhibitory and apoptosis-inducing action of tumor growth factor-beta; Indication that Runx3 is a major growth regulator of gastric epithelial cells.
ACCESSION #
9758395

 

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