HLA-DQ8 as an Ir gene in coeliac disease
- Toxic, Immunostimulatory and Antagonist Gluten Peptides in Celiac Disease. Silano, Marco; Vincentini, Olimpia; De Vicenzi, Massimo // Current Medicinal Chemistry;Apr2009, Vol. 16 Issue 12, p1489
Celiac disease (CD) is an increasingly diagnosed, permanent autoimmune enteropathy, triggered, in susceptible individuals, by the ingestion of gluten, the alcohol -- soluble protein fraction of some cereals, such as wheat, rye and barley. The main protein of wheat gluten is called gliadin, the...
- Probiotics, Prebiotics and Immunomodulation of Gut Mucosal Defences: Homeostasis and Immunopathology. Hardy, Holly; Harris, Jennifer; Lyon, Eleanor; Beal, Jane; Foey, Andrew D. // Nutrients;Jun2013, Vol. 5 Issue 6, p1869
Probiotics are beneficial microbes that confer a realistic health benefit on the host, which in combination with prebiotics, (indigestible dietary fibre/carbohydrate), also confer a health benefit on the host via products resulting from anaerobic fermentation. There is a growing body of evidence...
- Recent advances in gastrointestinal immunology. Materacki, Luke; Dulaimi, David Al // Gastroenterology & Hepatology from Bed to Bench;Winter2016, Vol. 9 Issue 1, p70
Several abstracts are presented related to gastrointestinal immunology including thymic stromal lymphopoietin expression in patients with coeliac disease, bacterial effect to the efficacy of chemotherapeutic drugs and stufy on gut DNA viromes in Malawian twins.
- Coeliac disease, mucosal change and IEL: doing what counts the best. Marsh, Michael N. // Gastroenterology & Hepatology from Bed to Bench;Winter2016, Vol. 9 Issue 1, p1
The author discusses his paper on research on coeliac disease that involved study on sequences of the gliadins and cognate proteins towards predicting likely immunogenic epitopes and considering possible polymorphisms in the HLA genes to those sensitised to gluten.
- Another tool to find refractory CD. // GIG Newsletter;Summer2008, Vol. 31 Issue 3, p34
The article focuses on a study which indicates that testing for serum immunoglobulin A (IgA) antibodies against calreticulin (CRT) and its selected peptide could be a very beneficial tool in diagnosing refractory celiac disease (RCD). It references a study published in the July 11, 2008 issue of...
- Presence of anti-‘tissue’ transglutaminase antibodies in inflammatory intestinal diseases: an apoptosis-associated event? Farrace, M G; Picarelli, A; Di Tola, M; Sabbatella, L; Marchione, O P; Ippolito, G; Piacentini, M // Cell Death & Differentiation;Jul2001, Vol. 8 Issue 7, p767
Presents letter to the editor published in the 2001 issue of 'Cell Death and Differentiation.' Description of Celiac disease (CD) as a permanent intolerance to gluten; Characterization of CD by a spectrum of lesions in the intestinal mucosa; Identification of tissue transglutaminase as the...
- Capsule endoscopy may allow early detection of overt lymphoma. // Hem/Onc Today;11/10/2012, Vol. 13 Issue 21, p55
The article reports on a study by Maximilien Barret, M.D., MSc, of Assistance Publique-Hopitauxde Paris and colleagues, concerning intestinal mucosa assessment through capsule endoscopy to accurately diagnose celiac disease and detect overt lymphoma.
- RÄ‚SPUNSUL IMUN IGE-MEDIAT ÃŽN BOALA CELIACÄ‚ LA COPIL. Samaşca, Gabriel; Dejica, Doru // Romanian Medical Journal;2010, Vol. 57 Issue 1, p66
Celiac disease appears when there is an inadequate immune response to gluten, a protein that finds itself in wheat. Adverse reactions to way may also be of allergic nature, because of the production of IgE antibodies against soluble proteins from wheat. The liaison between the two of them,...
- Rebutting Oberhuber-Again. Marsh, Michael N.; Johnson, Matt W.; Rostami, Kamran // Gastroenterology & Hepatology from Bed to Bench;Autumn2015, Vol. 8 Issue 4, p303
A letter to the editor is presented in which the author rebuts a study by researcher Oberhuber which suggests the existence "atrophic" and "partially degenerate" villi in celiac mucosae.