TITLE

Granular cell tumor of the sellar and suprasellar region: clinicopathologic study of 11 cases and literature review

AUTHOR(S)
Cohen-Gadol, Aaron A.; Pichelmann, Mark A.; Link, Michael J.; Scheithauer, Bernd W.; Krecke, Karl N.; Young Jr., William F.; Hardy, Jules; Giannini, Caterina; Young, William F Jr
PUB. DATE
May 2003
SOURCE
Mayo Clinic Proceedings;May2003, Vol. 78 Issue 5, p567
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Objective: To report a series of cases of surgically resected granular cell tumors in an attempt to better characterize their clinical presentation, imaging features, and treatment outcomes with attention to previously published literature. Patients and Methods: This is a retrospective study of 11 patients with granular cell tumors. Information obtained from patients' medical records was supplemented by direct physician and patient telephone contact. Results: The study group consisted of 9 women and 2 men, with a mean +/- SD age of 50 +/- 15 years (range, 26-73 years). Seven patients were symptomatic, 3 of whom presented with visual complaints. Four patients presented primarily with endocrine dysfunction (2) or headaches (2). The duration of symptoms varied from 1 to 12 months (mean +/- SD, 6.0 +/- 4.5 months). Formal visual field testing revealed bitemporal hemianopsia in 6 and a right-sided visual field deficit in 2. The tumor appeared as a well-defined, relatively homogeneously (6) or heterogeneously (1) enhancing suprasellar mass on contrast infusion. Tumor size varied from 1.5 to 6.0 cm (mean +/- SD, 3.1 +/- 1.6 cm). At surgery, the mass was noted to be firm and vascular, and in at least 3 patients these features prevented gross total resection. Only 1 patient who had undergone biopsy of his lesion received adjuvant radiation therapy. Follow-up was obtained in all but 1 patient. Nine of these 10 patients are alive and are either free of disease or have had no disease progression. Follow-up in these 9 patients varied from 1 to 16 years (mean +/- SD, 6.5 +/- 53 years). Conclusions: A granular cell tumor is generally a surprise finding in that it is seldom considered in the differential diagnosis of contrast-enhancing, demarcated sellar region masses. Granular cell tumors are benign and slow growing with no pronounced tendency for invasion or recurrence. Because of the indolent growth of granular cell tumors, the surgical goal of tumor decompression is a reasonable therapeutic approach.
ACCESSION #
9749434

 

Related Articles

  • Meckel's diverticulum: A ten-year experience. Arnold, Jame F.; Pellicane, James V. // American Surgeon;Apr1997, Vol. 63 Issue 4, p354 

    Seeks to identify factors suggestive of the need for surgical therapy and the associated morbidity and morality of resection. Information on the most common congenital anomaly of the small intestine; Findings from a number of case studies carried out.

  • Excision in Senegal--information for action.  // Women's International Network News;Autumn90, Vol. 16 Issue 4, p33 

    Reports on the practice of excision in Senegal according to a report by the Environment and Development in the Third World. Areas of Senegal where excision is practiced; Average age where excision is practiced; Excision as a village rite.

  • The fusiform excision. Zuber, Thomas J.; Dewitt, Donald E. // American Family Physician;2/1/1994, Vol. 49 Issue 2, p371 

    Presents the procedure for fusiform excision of a skin lesion. Classic fusiform excision technique; Hematomas st the base of an excision; Design and performance of an excision; Undermining and wound closure.

  • PRELIMINARY OUTCOMES AFTER TOTAL MESORECTAL EXCISION (TME) WORKSHOPS IN BC.  // Canadian Journal of Surgery;Aug2006 Supplement, Vol. 49, p7 

    An abstract of the article "Preliminary Outcomes After Total Mesorectal Excision (TME) Workshops in BC," by P. T. Phang, H. Kennecke, J. K. MacFarlane, K. Ng, G. McGregor, T. Strack, D. DesLauriers and J. H. Hay is presented.

  • Correction.  // Canadian Journal of Surgery;Jun2008, Vol. 51 Issue 3, p226 

    A correction to the article "Role of the endo-GIA stapler in transanal excision of rectal tumours" that was published in the April 2008 issue is presented.

  • Papilliferous Keratoameloblastoma of Mandible: A Papillary Ameloblastic Carcinoma. Collini, Paola; Zucchini, Nicola; Vessecchia, Graziella; Guzzo, Marco // International Journal of Surgical Pathology;Apr2002, Vol. 10 Issue 2, p149 

    Presents a case of papilliferous keratoameloblastoma. Resection of a right mandibular neoplasm infiltrating bone and soft tissues; Characteristics of the cysts; Presence of cribriform, solid and tubular patterns.

  • Fusiform Excision. Zuber, Thomas J. // American Family Physician;4/1/2003, Vol. 67 Issue 7, p1539 

    Provides information on the fusiform excision technique used by physician for removing skin and subcutaneous lesions. Methods and materials in fusiform excision; Procedure description of fusiform excision; Complications from fusiform excision.

  • Information from Your Family Doctor: Fusiform Excision Procedure.  // American Family Physician;4/1/2003, Vol. 67 Issue 7, 'Special section' p1553 

    Provides information on fusiform excision procedure. Background on fusiform excision biopsy; Advantages over circle excision; Complications after fusiform excision biopsy; Care for a sutured incision.

  • He thought his arms would be taken off. Mandal, Lal B. // Pulse;2/23/2011, Vol. 71 Issue 7, p14 

    A letter to the editor in presented which discusses an excision of a patient' s nail at the Sussex Orthopaedic Hiospital. .

  • Complication after treatment.  // GP: General Practitioner;10/14/2002, p76 

    Presents various complications in patients after surgery. Results of a total nail bed excision on a patient's finger; Medical complication in a patient after a tooth brace fitting; Result of an incomplete excision of the nail bed in a patient's finger.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics