67-Year-Old Man With Hepatitis C Infection and Abdominal Distention
- US reports increase in liver cancer. Gottlieb, Scott // BMJ: British Medical Journal (International Edition);03/20/99, Vol. 318 Issue 7186, p755
Reports on the increase incidence of hepatocellular carcinoma in the United States. Percentage increase from 1976 to 1995; Main risk factors associated with hepatocellular carcinoma; Belief of many older Americans with hepatitis C on how the disease is contracted.
- Type C chronic hepatitis with the discovery of a small hepatocellular carcinoma 7 years after successful interferon therapy. Tomimatsu, Masahiko; Endo, Hitoshi; Kitazawa, Misa; Iga, Daijiro; Fujimoto, Tomoko; Ohkawa, Shin-Ichiro; Kajiyama, Hideki; Katagiri, Satoshi; Harada, Nobuhiko; Yamamoto, Masakazu; Takasaki, Ken // Journal of Gastroenterology;2003, Vol. 38 Issue 4, p395
The patient, a 61-year-old man, had sustained injuries in a traffic accident at the age of 26, for which he received a blood transfusion. Since 1988 (age, 49 years), abnormal hepatic function had been detected, and, because of the presence of hepatitis C virus antibodies, he was diagnosed as...
- HCV protein causes cancer. // AIDS Patient Care & STDs;Dec98, Vol. 12 Issue 12, p943
Discusses findings of Japanese researchers that the hepatitis C virus (HVC) core protein induces hepatocellular carcinoma. Development of hepatic steatosis in laboratory mice as histologic feature of chronic hepatitis C; Characteristics of mice carrying HCV envelope genes.
- Incomplete response of interferon treatment has an important role for the prevention of hepatocellular carcinoma. Hayashi, Norio // Journal of Gastroenterology;1999, Vol. 34 Issue 5, p655
Editorial. Focuses on the incidence of hepatocellular carcinoma (HCC) in Japan. Incidence rate of HCC in cirrhotic patients with antibodies to hepatitis C virus (HCV); Treatment of HCV.
- Iron, hepatitis C virus, and hepatocellular carcinoma: iron reduction preaches the gospel for chronic hepatitis C. Fujita, Naoki; Takei, Yoshiyuki // Journal of Gastroenterology;Nov2007, Vol. 42 Issue 11, p923
The article discusses various reports publishes within the issue, including one on chronic hepatitis C virus and another on iron reduction.
- An Unusual Presentation of Hepatocellular Carcinoma. Fitzmorris, Paul Stephen; Morris, Jason L; Fettig, David Michael // American Journal of Gastroenterology;Oct2015, Vol. 110 Issue 10, p1395
A case study of 59-year-old man with a history of hepatitis C and alcoholic cirrhosisis presented, and mentions that upon fine-needle aspiration of the mass revealed hepatocellular carcinoma.
- Accumulation of 8-n itroguanine in the liver of chronic hepatitis C patients without sustained virological response after completion of interferon therapy. Kaito, Masahiko; Horiike, Shinichiro; Tanaka, Hideaki; Fujita, Naoki; Adachi, Yukihiko // Journal of Gastroenterology;Jul2006, Vol. 41 Issue 7, p713
The article describes the use of 8-nitroguanine as a biomarker for evaluating the severity of hepatitis C virus-induced chronic inflammation in relation to hepatocellular carcinoma. Interferon therapy was found to decrease the accumulation of 8-nitroguanine in the liver. This suggests that...
- The role of hepatitis C virus in the pathogenesis of hepatocellular carcinoma. Tran, Gui // Bioscience Horizons: The National Undergraduate Research Journal;Jun2008, Vol. 1 Issue 2, p167
Hepatitis C virus (HCV) is a worldwide pandemic, chronically affecting over 170 million people worldwide. It is a major risk factor for the development of hepatocellular carcinoma (HCC) and there is increasing experimental evidence to suggest that the virus plays a direct role in neoplastic...
- Discovery of Small-Molecule Inhibitors of HCV NS3-4A Protease as Potential Therapeutic Agents against HCV Infection. Shu-Hui Chen; Seng-Lai Tan // Current Medicinal Chemistry;2005, Vol. 12 Issue 20, p2317
Chronic infection with hepatitis C virus (HCV) is associated with liver cirrhosis that often leads to hepatic failure and hepatocellular carcinoma (HCC). HCV infection has become a global health threat and the main cause of adult liver transplants in developed nations. Current approved anti-HCV...