Ahmed, Z.; Ahmed, S.; Hawkes, N.D.
April 2003
Gut;Apr2003 Supplement 1, Vol. 52, pA108
Academic Journal
Aims: To assess changes in mortality from liver disease across the Principality of Wales over the past decade, and to relate these changes to published figures on alcohol consumption by region. Methods: Deaths from liver disease were identified from public health mortality files supplied by the Office for National Statistics, searching lCD-9 reference codes 570-573 for regions throughout Wales between 1991-2000. Population data for the corresponding regions during this time period were also provided. Data on alcohol consumption by region were obtained from the Welsh Health Survey (1995 and 1998). Data are presented for the quinquennio, 1991-5 and 1996-2000. Results: In all regions mortality from liver disease has increased in the second quinquennium (see Table). There is a significant correlation between liver mortality rates and published data on the proportion of the respective populations consuming alcohol above recommended levels Spearman's test, r = 0.484, p= 0.022). Conclusions: All regions of Wales have seen a modest increase in mortality from liver disease over the past 5 years—not to the extent of that reported from the West Midlands (threefold increase). Increased mortality rates were seen in areas of high alcohol consumption. Anecdotally alcoholic liver disease remains the major cause ordeath from liver disease in Wales, the contribution of genetic and racial background and chronic HCV infection require further examination.


Related Articles

  • Predicting mortality by the Glasgow alcoholic hepatitis score: the long awaited progress? Tilg, H.; Kaser, A. // Gut;Aug2005, Vol. 54 Issue 8, p1057 

    The new Glasgow alcoholic hepatitis score may represent a substantial improvement in clinical phenotyping and could catalyse the development of new treatments in severe alcoholic hepatitis.

  • Can Ireland's Increased Rates of Alcoholic Liver Disease Morbidity and Mortality be Explained by Per Capita Alcohol Consumption? Mongan, Deirdre; McCormick, P. Aiden; O'Hara, Sinead; Smyth, Bobby; Long, Jean // Alcohol & Alcoholism;Jul/Aug2011, Vol. 46 Issue 4, p500 

    A letter to the editor is presented which discusses the impact of per capita alcoholic beverage consumption on morbidity and mortality rates related to alcohol liver disease among Irish people.

  • Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score. Forrest, E. H.; Evans, C. D. J.; Stewart, S.; Phillips, M.; Oo, Y. H.; McAvoy, N. C.; Fisher, N. C.; Singhal, S.; Brind, A.; Haydon, G.; O'Grady, J.; Day, C. P.; Hayes, P. C.; Murray, L. S.; Morris, A. J. // Gut;Aug2005, Vol. 54 Issue 8, p1174 

    Introduction: Alcoholic hepatitis is associated with a high short term mortality. We aimed to identify those factors associated with mortally and define a simple score which would predict outcome in our population. Methods: We identified 241 patients with alcoholic hepatitis. Clinical and...

  • Has mortality related to alcohol decreased in Sweden? Romelsjo, Anders; Agren, Gunnar // British Medical Journal (Clinical Research Edition);7/20/1985, Vol. 291 Issue 6489, p167 

    Presents a study on the mortality rate related to alcohol in Sweden. Effects of a decrease in the consumption of alcohol on deaths related to alcohol; Information on live cirrhosis and pancreatitis; Diagnosis of alcoholic psychosis, alcoholism and alcohol intoxication in persons with...

  • Alcohol and the emergency service patient. Holt, S.; Stewart, I.C.; Dixon, J.M.; Elton, R.A.; Taylor, T.V.; Little, K. // British Medical Journal;9/6/1980, Vol. 281 Issue 6241, p638 

    Determines the prevalence of alcohol use in casualty patients breath-alcohol analysis. Role of alcohol abuse in mortality and morbidity from road traffic, industrial and recreational accidents; Unreliability of clinical diagnosis of alcohol intoxification; Effects of alcohol on...

  • Racial Difference in Mortality Among U.S. Veterans with HCV/HIV Coinfection. Merriman, Nathan A.; Porter, Steven B.; Brensinger, Colleen M.; Reddy, K. Rajender; Kyong-Mi Chang // American Journal of Gastroenterology;Apr2006, Vol. 101 Issue 4, p760 

    OBJECTIVES: This study was performed to examine the impact of viral coinfections and race on clinical and virological outcome of hepatitis C virus (HCV) infection. METHODS: Three groups of patients (265 HCV/HIV coinfected, 251 HCV monoinfected, 227 HIV monoinfected) were identified between 2000...

  • Mortality among Paris sewage workers. Wild, P.; Ambroise, D.; Benbrik, E.; Tiberguent, A.; Massin, N. // Occupational & Environmental Medicine;Mar2006, Vol. 63 Issue 3, p168 

    Objectives: To describe the mortality of Paris sewage workers. Methods: A cohort of all Paris sewage workers since 1970 was established and followed up in mortality until 1999. The causes of death were determined by matching with a national database. The mortality rates were compared to the...

  • Preventive care in chronic liver disease. Riley, Thomas R.; Smith, Jill P.; Riley, T R; Smith, J P // JGIM: Journal of General Internal Medicine;Nov1999, Vol. 14 Issue 11, p699 

    Objective: To identify preventive care measures that are appropriate for and specific to patients with chronic liver disease and to provide recommendations and information that can be shared with patients. Measurements: A review of the literature was undertaken using...

  • Journals Watch: Tea is good for your liver.  // GP: General Practitioner;12/23/2005, p2 

    The article reports on the findings of a research conducted in the U.S. Researchers found that excessive drinkers of alcohol developed chronic liver disease at half the rate of those whose daily tea intake was lower.


Read the Article


Sign out of this library

Other Topics