IDENTIFICATION OF CORTICOSTEROID RESPONDERS IN THE TREATMENT OF ACUTE ALCOHOLIC HEPATITIS
- The Glasgow alcoholic hepatitis score identifies patients who may benefit from corticosteroids. Forrest, E. H.; Morris, A. J.; Stewart, S.; Phillips, M.; Oo, Y. H.; Fsher, N. C.; Haydon, G.; O'grady, J.; Day, C. P. // Gut;Dec2007, Vol. 56 Issue 12, p1743
Introduction: There is no consensus on the pharmacological treatment of alcoholic hepatitis. The Glasgow alcoholic hepatitis score (GAHS) has been shown to be more accurate than the modified Maddrey's discriminant function (mDF) in the prediction of outcome from alcoholic hepatitis. This study...
- Methylprednisolone Therapy in Patients with Severe Alcoholic Hepatitis. Carithers Jr., Robert I.; Herlong, Franklin; Diehl, Anna Mae; Shaw, Ellen W.; Combes, Burton; Fallon, Harold J.; Maddrey, Willis C. // Annals of Internal Medicine;5/1/89, Vol. 110 Issue 9, p685
Presents a study that determined the efficiency of a corticosteroid in reducing the short-term mortality of patients with severe alcoholic hepatitis. Design of the study; Setting of the study; Profile of patients; Discussion on the results of the study.
- Do Corticosteroids Reduce Mortality from Alcoholic Hepatitis? Imperiale, Thomas F.; McCullough, Arthur J. // Annals of Internal Medicine;8/15/90, Vol. 113 Issue 4, p299
Presents a study that determined whether corticosteroids affect short-term mortality from alcoholic hepatitis. Overview of alcoholic hepatitis; Criteria used to assess the included trials; Assessment of the statistical validity of aggregating the trials; Mortality rates in treatment and control...
- THE TREATMENT OF ALCOHOLIC HEPATITIS. MORGAN, MARSHA Y. // Alcohol & Alcoholism;Mar1996, Vol. 31 Issue 2, p117
Alcoholic hepatitis is a precirrhotic lesion; it develops in only a minority of chronic alcohol abusers even after decades of abuse The clinical spectrum of disease varies from asymptomatic hepatomegaly to florid hepatocellular failure with gastrointestinal bleeding and hepatic encephalopathy....
- Methylprednisolone. // Reactions Weekly;5/8/2010, Issue 1300, p34
The article describes the case of a nine-year-old boy who developed fulminant herpes simplex hepatitis while receiving treatment with methylprednisolone for status asthmaticus and pneumonia.
- Metabolism of vehicle alcohol affects Asian response to topical corticosteroids. Guttman, Cheryl // Dermatology Times;Sep2001, Vol. 22 Issue 9, p23
Reports the effects of vehicle alcohol metabolism on topical corticosteroid response among Asian patients in the United States. Influence of alcohol vehicle on the skin blanching response of patients; Effects of alcohol on pharmacodynamic response; Quantification of drug penetration into the...
- THE GLASGOW ALCOHOLIC HEPATITIS SCORE IDENTIFIES PATIENTS LIKELY TO BENEFIT FROM CORTICOSTEROIDS. Forrest, E. H.; Morris, J. M.; Stewart, S.; Day, C. P. // Gut;Apr2004 Supplement 3, Vol. 53, pA13
The use of corticosteroids in the treatment acute alcoholic hepatitis remains controversial. Their use has been recommended for patients with a discriminant function. The recently described Glasgow Alcoholic Hepatitis Score (GAHS) appears to have a greater accuracy in predicting patient outcome....
- Alcoholic Hepatitis: Current Management. Spengler, Erin; Dunkelberg, Jeffrey; Schey, Ron // Digestive Diseases & Sciences;Oct2014, Vol. 59 Issue 10, p2357
Alcoholic hepatitis is an acute manifestation of alcoholic liver disease with mortality as high as 40-50 % in severe cases. Patients usually have a history of prolonged alcohol abuse with or without a known history of liver disease. Although there is significant range in severity at...
- Young men with bilateral pain in the lower part of patella. Vreju, Florin // Medical Ultrasonography;Sep2013, Vol. 15 Issue 3, p250
The quiz on case study of a 34 years old male patient with autoimmune hepatitis and treated with high dose of corticosteroids is presented.