MAKING THE DIAGNOSIS OF COELIAC DISEASE: IS THERE A ROLE FOR PUSH ENTEROSCOPY?
- Antibody testing tied to increased incidence of celiac disease. // Contemporary Pediatrics;Feb2010, Vol. 27 Issue 2, p17
The article discusses a study by K. E. McGowan et al, which found the connection between immunoglobulin A endomysial antibody (IgA-EMA) testing and celiac disease in children.
- Missing endomysial and reticulin binding of coeliac antibodies in transglutaminase 2 knockout tissues. Korponay-Szabó, I.R.; Laurila, K.; Szondy, Z.; Halttunen, T.; Szalai, Z.; Dahlbom, I.; Rantala, I.; Kovács, J.B.; Fésüs, L.; Máki, M. // Gut;Feb2003, Vol. 52 Issue 2, p199
Background: Autoantibodies against transglutaminase 2 (TG2) are thought to be responsible for the endomysial (EMA), reticulin (ARA), and jejunal antibody (JEA) tissue binding of serum samples from coeliac patients but the exclusive role of TG2 in these staining patterns has not yet been...
- The role of antitissue transglutaminase assay for the daignosis and monitoring of coeliac disease: a Frenchâ€”Italian muticentre study. Tonutti, E.; Visentini, D.; Bizzara, N.; Caradonna, M.; Cerni, L.; Villalta, D.; Tozzoli, R. // Journal of Clinical Pathology;May2003, Vol. 56 Issue 5, p389
Aims: Tissue transglutaminase (tTG) was recently identified as the major autoantigen in coeliac disease. The aim of this multicentre study was to evaluate the impact of a new immunoenzymatic assay for the detection of IgA anti-tGT antibodies. Methods: Seventy four Italian and French clinical...
- Authors' reply. Pearce, C.B.; Duncan, H.D.; Sinclair, D.; Poller, D.N. // Gut;Sep2002, Vol. 51 Issue 3, p455
Background: Hepatitis C virus (HCV) infection is a significant problem in the management of hoemodialysis patients. A high prevalence of HCV infection in haemodialysis patients has been reported. Risk factors such as the number of blood transfusions or duration on haemodialysis have been...
- Testing for Celiac Disease. Ferris, Mary Elina // Internal Medicine Alert;7/15/2010, Vol. 32 Issue 13, p99
Testing patients with abdominal symptoms for celiac disease in primary care settings using IgA tissue transglutaminase antibodies and IgA endomysial antibodies yielded high sensitivity and specificity, justifying their use widely for diagnosis.
- Anti-tissue transglutaminase antibodies from coeliac patients inhibit transglutaminase activity both in vitro and in situ. Esposito, C.; Paparo, F.; Caputo, I.; Rossi, M.; Maglio, M.; Sblattero, D.; Not, T.; Porta, R.; Auricchio, S.; Marzari, R.; Troncone, R. // Gut;Aug2002, Vol. 51 Issue 2, p177
Background and aims: Coeliac disease (CD) is a multifactorial disorder which has an autoimmune component characterised by the occurrence of disease specific autoreactive antibodies against the enzyme tissue transglutaminase (tTG). The aim of this study was to investigate whether binding of...
- Predictive value for coeliac disease of antibodies to gliadin, endomysium, and jejunum in patients attending for jejunal biopsy. McMillan, Stanley A.; Haughton, David J.; Biggart, J. Dennis; Edgar, J. David; Porter, Kenneth G.; McNeill, Thomas A. // BMJ: British Medical Journal (International Edition);11/9/91, Vol. 303 Issue 6811, p1163
Examines the predictive value for celiac diseases of antibodies in patients with jejunal biopsy. Detection of gliadin IgA in patients; Symptoms of the disease; Presence of endomysial antibodies found using indirect immunofluorescence.
- Antibody tests to simplify coeliac disease diagnosis. // Pulse;5/19/2010, Vol. 70 Issue 17, p9
The article focuses on the study conducted by primary care researchers at the University of Keele in Staffordshire, England concerning the effectiveness of gastrointestinal and serum antibody tests for coeliac disease diagnosis.
- Gliadin antibody levels: a serological test for coeliac disease. O'Farrelly, Cliona; Kelly, J.; Hekkens, W.; Bradley, B.; Thompson, A.; Feighery, C.; Weir, D.G. // British Medical Journal (Clinical Research Edition);6/25/1983, Vol. 286 Issue 6383, p2007
Assesses the diagnostic value in coeliac disease of circulating antibodies to casein, crude and alpha gliadin. Adaptation of the enzyme linked immunosorbent assay system; Validity of the serological test; Increase in the levels of alpha gliadin antibody.