TITLE

SMOKING IS ASSOCIATED WITH THE DEVELOPMENT OF POST-INFECTIOUS IRRITABLE BOWEL SYNDROME

AUTHOR(S)
Parry, S.D.; Barton, J.R.; Welfare, M.R.
PUB. DATE
April 2003
SOURCE
Gut;Apr2003 Supplement 1, Vol. 52, pA84
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Introduction: Irritable bowel syndrome (lBS) can be triggered by psychological stress, alterations in gut motor function and/or visceral perception. Previous studies suggest 4-32% of people develop lBS after bacterial gastroenteritis but the exact mechanisms underlying post-infectious lBS are not clear. Aim: To look into the role of possible causative factors in the development of post-infectious functional gastrointestinal disorders, namely lBS, functional dyspepsia, or functional diarrhoea. Methods: A prospective cohort study. There were 128 subjects without a prior FGID under study and with recent stool positive bacterial gastroenteritis who consented to participate. The presence or not of lBS, functional dyspepsia or functional diarrhoea was diagnosed at the start and on follow up at 6 months using self-complete Rome II modular questionnaires. Data on demographics, social class, infecting organism, smoking and alcohol use, anxiety, depression (via Hospital Anxiety and Depression Scale) and life events and impact (via LiFe Events Survey) were collected at the start of the study. Results: One hundred and seven Rome II questionnaires were returned at follow up. Twenty-five subjects developed a FGID, 16 who had symptoms consistent with lBS. Of the factors mentioned, only smoking was significantly associated with the development of a postinfectious FGID (odds ratio 4.1; CI 1.4 to 11.6). The odds ratio of a smoker developing post-infectious lBS was 3.6 (CI 1.12 to 11.60). The odds ratios of a smoker developing functional diarrhoea or functional dyspepsia were not statistically significant. Conclusion: Post-infectious lBS appears to be associated with smoking and we did not find evidence of association with life events, anxiety, or depression. Smoking is known to moderate gut immunity in other disorders such as ulcerative colitis and Crohn's disease. Our study adds to increasing evidence for an organic basis to post-infectious lBS, perhaps moderated via...
ACCESSION #
9747848

 

Related Articles

  • Irritable bowel syndrome patients show enhanced modulation of visceral perception by auditory stress. Dickhaus, Britta; Mayer, Emeran A.; Firooz, Nazanin; Stains, Jean; Conde, Francisco; Olivas, Teresa I.; Fass, Ronnie; Chang, Lin; Mayer, Minou; Naliboff, Bruce D. // American Journal of Gastroenterology;Jan2003, Vol. 98 Issue 1, p135 

    : ObjectivesSymptoms in irritable bowel syndrome (IBS) patients are sensitive to psychological stressors. These effects may operate through an enhanced responsiveness of the emotional motor system, a network of brain circuits that modulate arousal, viscerosomatic perception, and autonomic...

  • REACH FOR THE SKY. Greenhalgh, Trisha // Accountancy;Nov97, Vol. 120 Issue 1251, p32 

    Provides information on irritable bowel syndrome. Role of psychological stress in triggering the symptoms; Three types of irritable bowel syndrome; Predominant symptoms; Treatment.

  • Prognosis in post-infective irritable bowel syndrome: a six year follow up study. Neal, K.R.; Barker, L.; Spiller, R.C. // Gut;Sep2002, Vol. 51 Issue 3, p410 

    Background: Refractory sprue is defined as primary or secondary failure to respond to a gluten free diet in patients with coeliac disease-like enteropathy and may signify cryptic or overt enteropathy associated T cell lymphoma. Aims: To study in detail jejunal morphology and immunophenotypes in...

  • The Relationship Between Daily Life Stress and Gastrointestinal Symptoms in Women with Irritable Bowel Syndrome. Levy, Rona L.; Cain, Kevin C.; Jarrett, Monica; Heitkemper, Margaret M. // Journal of Behavioral Medicine;Apr97, Vol. 20 Issue 2, p177 

    Research on irritable bowel syndrome (IBS), a functional disorder of the gastrointestinal (GI) system, has linked GI symptoms to stress. This study examined the relationship between daily stress and GI symptoms across women and within woman in IBS patients ( n = 26), IBS nonpatients (IBS-NP; n =...

  • Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study. Rodriguez, Luis A. Garcia; Ruigomez, Ana // BMJ: British Medical Journal (International Edition);02/27/99, Vol. 318 Issue 7183, p565 

    Provides information on a study which examined the increased risk of irritable bowel syndrome after an episode of bacterial gastroenteritis. Information on the study participants; Characteristics of study cohorts and incidence and relative risk of irritable bowel syndrome associated with...

  • Does bacterial gastroenteritis predispose people to functional gastrointestinal disorders? A prospective, community-based, case—control study. Parry, Sally D.; Stansfield, Rosamund; Jelley, Diana; Gregory, Wendy; Phillips, Elizabeth; Barton, J. Roger; Welfare, Mark R. // American Journal of Gastroenterology;Sep2003, Vol. 98 Issue 9, p1970 

    : ObjectivesIrritable bowel syndrome (IBS) might develop after gastroenteritis. Most previous studies of this relationship have been uncontrolled, and little is known regarding other functional gastrointestinal disorders (FGIDs) after gastroenteritis. The primary aim of this study was to...

  • Additional research needed of post-infectious irritable bowel syndrome. DuPont, Herbert L. // Infectious Disease News;Jul2013, Vol. 26 Issue 7, p8 

    The author asserts the importance of further studies concerning post-infectious irritable bowel syndrome (PI-IBS), a condition in which IBS occurs following a bout of diarrhea or gastroenteritis amid the presence of biochemical, inflammatory and gut motor defects.

  • BALANCE YOUR BODY.  // Women's Fitness;May2015, Issue 139, p92 

    The article offers information about Irritable Bowel Syndrome( IBS). The symptoms include bloating, abdominal cramping, constipation and diarrhoea. It is intrusive to day-to-day life and can be a embarrassing at times. Stressful situations create bad eating habits and led to disruption to the...

  • FUNCTIONAL BOWEL DISORDERS. Ruckert, Linden; Aziz, Qasim // Pulse;7/30/2008, Vol. 68 Issue 26, p18 

    The article presents several questions and answers related to medicine, including the role of stress, diagnosis of irritable bowel syndrome and use of probiotics.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics