EVIDENCE FOR INCREASED POST-PRANDIAL PLASMA 5-HYDROXYTRYPTAMINE (5-HT) CONCENTRATION IN FUNCTIONAL DYSPEPTICS AND RELATIONSHIP TO GENDER AND SYMPTOMS
- Of actors, bolting horses, and rops in oceans! Cremonini, F.; Camilleri, M. // Gut;May2003, Vol. 52 Issue 5, p619
Examines whether serotonin mediates postprandial symptoms in irritable bowel syndrome (IBS). Components of the colonic contractile response to meals of IBS patients; Reasons behind the differences in circulating serotonin levels in IBS.
- Increased platelet depleted plasma 5-hydroxytryptamine concentration following meal ingestion in symptomatic female subjects with diarrhoea predominant irritable bowel syndrome. Houghton, L.A.; Atkinson, W.; Whitaker, R.P.; Whorwell, P.J.; Rimmer, M.J. // Gut;May2003, Vol. 52 Issue 5, p663
Background: Meal ingestion is often associated with exacerbation of gastrointestinal symptoms in subjects with irritable bowel syndrome (lBS). Furthermore, recent preliminary data suggest that 5-hydroxytryptamine (5-HT) concentration in platelet poor plasma is elevated following meal ingestion...
- Serotonin's Role in IBS. // BioWorld Today;5/10/2010, Vol. 21 Issue 89, Special section p2
The article reports on the serotonin gene variants identified by a research team at Mayo Clinic which impact irritable bowel syndrome (IBS).
- Incidence of colonic ischemia, hospitalized complications of constipation, and bowel surgery in relation to use of alosetron hydrochloride. Miller, David P.; Alfredson, Tanya; Cook, Suzanne F.; Sands, Bruce E.; Walker, Alexander M. // American Journal of Gastroenterology;May2003, Vol. 98 Issue 5, p1117
: ObjectiveAlosetron hydrochloride (Lotronex), a potent selective 5-hydroxytryptamine3 receptor antagonist, was approved in February, 2000 in the United States for the treatment of diarrhea-predominant irritable bowel syndrome (IBS) in women. Marketing was suspended in November, 2000, after...
- Tegaserod: A Viewpoint by Peter J. Whorwell. Whorwell, P.J. // Drugs;Sep1999, Vol. 58 Issue 3, p497
Comments on a study on the use of serotonin drug in the treatment of irritable bowel syndrome (IBS). Background of IBS; Use of tegaserod in the treatment of IBS; Problems regarding the development of drugs for the treatment of IBS.
- Tegaserod: A Viewpoint by M. Scott Harris. Harris, M.S. // Drugs;Sep1999, Vol. 58 Issue 3, p497
Discusses a study on the use of tegaserod serotonin drug in the treatment of irritable bowel syndrome. Symptoms and manifestation of the disease; Diagnosis and treatment; Mechanism of action of tegaserod.
- Tegaserod. Scott, L.J.; Perry, C.M. // Drugs;Sep1999, Vol. 58 Issue 3, p491
â–´ Tegaserod is a serotonin (5-hydroxytryptamine; 5-HT) receptor partial agonist which has been investigated for the treatment of irritable bowel syndrome (IBS). Specifically, it binds with high affinity to human 5-HT receptors, thereby stimulating the release of neurotransmitters and the...
- Diet Spells R-E-L-l-E-F from IBS. Palmer, Sharon // Environmental Nutrition;Oct2011, Vol. 34 Issue 10, p1
The article offers information on the symptoms, diagnosis and treatment of irritable bowel syndrome (IBS). It says that abdominal pain, constipation and diarrhea are some of the common symptoms experienced by IBS patients. The diagnosis of the disease is based on recurrent abdominal pain and...
- Ranking of symptoms by patients with the irritable bowel syndrome. Maxton, D.G.; Morris, J.A.; Whorwell, P.J. // BMJ: British Medical Journal (International Edition);11/4/89, Vol. 299 Issue 6708, p1138
Examines the symptoms of irritable bowel syndrome among patients in Great Britain. Main symptoms of the bowel syndrome; Prevalence of non-colonic symptoms; Advice on the management of the symptoms.