Rayner, C.K.; Kamm, M.A.; Knowles, C.H.; Scott, S.M.; Lunniss, P.J.
April 2003
Gut;Apr2003 Supplement 1, Vol. 52, pA84
Academic Journal
Colonic transit is delayed in about half of patients presenting to specialist units with severe constipation. Most patients are female, and a majority (about two thirds) have no identifiable cause. There is almost no information regarding males with slow transit constipation. We reviewed the records of patients with constipation referred to two large centres specialising in functional bowel disorders, over 4 years (Centre 1) and 8 years (Centre 2) respectively. Colonic transit was assessed by validated radiological marker studies. Constipation was considered idiopathic when dilated bowel (megarectum) and neurologic injury (central, spinal, or pelvic) were excluded. See Table 1. Not only were the minority of patients referred for constipation male, but proportionally fewer males than females had slow colonic transit (* p 0.05). Of males w,th slow transit, only 8 from Centre 1 and 2 from Centre 2, were idiopathic (10 of 43, or 23%) (see Table 2). In the small number of males presenting with constipation, colonic transit is delayed in the minority, and most of these have an identifiable cause, in distinction to women. Either men are less exposed to insults that impair colonic function, or have a greater reserve in resisting their effects.


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