Bassi, A.; Brown, E.; Bodger, K.
April 2003
Gut;Apr2003 Supplement 1, Vol. 52, pA69
Academic Journal
Introduction: Studies of HR-QoL aim to assess the influence of disease on patients' lives by seeking patient-perceived valuations of health across discrete domains including physical and psychosocial function. The aim of the present study was to measure HR-QoL in an unselected cohort of IBD patients and to correlate with demographics, disease type, extent and severity. Methods Subjects: We identified a 6-month prevalence cohort of 479 IBD patients receiving any form of care for IBD at our centre by cross referencing multiple hospital databases (out-patient letters, in-patient coding, diagnostic reports). Disease type, extent and severity (using a published grading system) were abstracted from casenotes. Postal survey: Self-administered questionnaire, the UK-IBDQ (modified to include an item about interference with household or recreational activities). The IBD-Q has 5 domains (Social; Emotional; Bowel 1; Bowel 2 & Systemic). Data analysed by linear regression. Results: 233 (48.6%) responded (CD n=87, UC n=122, indeterminate colitis n=24). Data incomplete in 12. Mean age (sex): CD 48.5 yrs (28 male); UC 48 yrs (61 male). Table summarises total QoL scores (% optimal function). Total scores for UC were higher than CD (76% v 70%, p<0.001) and lowest domain scores were in the Systemic domain (CD 55%; UC 64%). Emotional (p=0.011) and Bowel (p=0.03) scores were significantly lower in younger patients. Mean lost days from household / recreational activities in 6 months: CD21 d;UC 12d. Conclusions: Disease severity is the main determinant of overall QoL in IBD with greatest impact being on systemic well-being. QoL scores were lower in CD than UC overall and CD sufferers had greater loss of "social" days. Younger age is associated with lower ratings for emotional functioning.


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