TITLE

Evolution of endoscopic incidence of gastroduodenal ulcer (GDU) and esophagitis (E) after the wide application of Helicobacter pylori (Hp) eradication regimens

AUTHOR(S)
Michopoulos, S.; Sotiropoulou, M.; Petraki, K.; Natsios, A.; Katsakos, N.; Manthos, G.; Stamatis, G.; Zissis, M.; Kralios, N.
PUB. DATE
September 2002
SOURCE
Gut;Sep2002 Supplement 2, Vol. 51, pA62
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
There are several recent reports suggesting a decrease in the incidence of GDU. The aim of our study was to evaluate if there are changes in the prevalence of endoscopic diagnosis of GDU or E after the wide application of Hp eradication regimens. Patients & Methods: We analyzed all the endoscopic reports and related files of all the patients who had an UGI endoscopy during the years 1993, 1997 and 2001. Our department is situated in a central hospital of Athens, it belongs to the National Health System (NHS) and it has an open access for all beneficiaries of NHS. Results: Total number of fiberoscopies (UGI), gastric/duodenal ulcers (GDU) and E with the corresponding LA classification (A/B/C/D) are shown on the table. The groups were comparable for age, tobacco and alcohol consumption. Valuable information on Hp status in patients with endoscopic lesions were available in only 58% during 1993, while this increased dramatically during 1997 (96%) and 2001 (97%). Among them the % of Hp(+) patients was 50%, 42% and 51% for E, 77%, 65% and 73% for GU and 90%, 89% and 85% for DU for the 3 periods respectively. NSAID's consumption was not modified according to the files' data. Complications decreased only in 2001 (205, 196, 68). Conclusions: Since 1993, 1) The total number of UGI procedures has not changed, 2) The accurate control on Hp status has dramatically increased, 3) Neither the prevalence of GDU and E at endoscopy nor their Hp status were modified, 4) Non variceal hemorrhage decreased during 2001, regardless of the same NSAID's consumption.
ACCESSION #
9747655

 

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