TITLE

A PROSPECTIVE RANDOMIZED COMPARISON OF 10 FR VERSUS 7 FR BIPOLAR ELECTROCOAGULATION CATHETER IN COMBINATION WITH ADRENALINE INJECTION IN THE ENDOSCOPIC TREATMENT OF BLEEDING PEPTIC ULCERS

AUTHOR(S)
Paspatis, G.A.; Charoniti, I.; Papanikolaou, N.
PUB. DATE
April 2003
SOURCE
Gut;Apr2003 Supplement 1, Vol. 52, pA27
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background and Aims: Our study sought to compare the efficacy of bipolar electrocoagulation (gold probe) with 10 Fr (Group A) versus 7 Fr (Group B) catheter following adrenaline injection in the treatment of bleeding peptic ulcers. To the best of our knowledge, this is the only prospective, randomised study in humans. Methods: 77 consecutive patients with endoscopic evidence of peptic ulcer with active bleeding or a non-bleeding visible vessel were randomly assigned to one of the above protocols. 39 patients (31 males, 8 females, mean age 62 years) were included in group A and 38 (28 males, 10 females, mean age 61 years) in group B. Results: The initial haemostasis rate, rebleeding rate, duration of hospital stay, volume of blood transfused, number of operations needed, and number of deaths were not significantly different between the two groups. The mean number of electrocoagulations and the subsequent mean duration of electrocoagulations were significantly higher in group B patients (7.0±3.8, 14.1±7.6 seconds, respectively) compared with those of group A (4.6±2.6, 9.3±5.3 seconds, respectively) (p < 0.01). Multivariate stepwise logistic regression analysis revealed that among sex, age, location of bleeding, ulcer size, endoscopic severity of bleeding, and the size of the gold probes, the endoscopic severity of the bleeding, the small size of the gold probe, and the increased ulcer size were the only factors significantly associated with an increased number of electrocoagulations (Χ² = 31.1, p < 0.01, Χ² = 23.9, p < 0.01 and Χ² = 13.4, p < 0.01, respectively). Conclusions: Our data suggest that the use of the large size gold probe was significantly associated with a decreased number of electrocoagulations resulting in the reduction of electrocuagulation duration.
ACCESSION #
9747436

 

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