Thompson, A.A.; Park, K.P.
April 2003
Gut;Apr2003 Supplement 1, Vol. 52, pA21
Academic Journal
The Scottish Audit of Gastric and Oesophageal Cancer prospectively collected population based data on 3293 cancers diagnosed over a 2 year period with a minimum 1 year follow up. One aim of the project was to examine whether hospital size was related to outcome. The 53 contributing hospitals were divided by caseload, with small hospitals having significantly less delay in diagnosis than larger institutions (p = 0.001). However, this did not significantly improve subsequent survival (see Table 1). There was no statistically significant difference in postoperative mortality for either gastric or oesophageal cancer by hospital size (Table 2). Overall survival was 32% at 1 year [54% for surgical patients) and 17% at 2 years (33% for surgical patients). The factors adversey affecting survival by multivariate analysis in the surgical patients were American Society of Anaesthesiologists grade 4 (Hazard Ratio 1.35, CIs 1.00 to 1.81, p = 0.047) or 5 (HR 2.46, CI 1.42 to 4.27, p = 0.001) and margin involvement by tumour (HR 1.97 CI 1.32 to 2.96, p = 0.001). Conversely, non-smokers (HR 0.78, CI 0.64 to 0.94, p = 0.01), patients with junctional cancers (HR 0.7, CI 0.51 to 0.95, p = 0.021), and those with a history of H pylori infection (HR 0.79, CI 0.63 to 0.99, p = 0.04) did better. Following univariate, case mix adjusted and multivariate analysis, there was no difference in survival according to the size of the hospital oF presentation or hospital of surgery. In combination with data emerging from elsewhere, the guidance on the organisation of oesophago-gastric cancer services in the UK should be reviewed.


Related Articles

  • Early detection = protection. Ferguson, Teal; DeCoster, Roy // All Hands;Sep95, Issue 941, p40 

    Emphasizes the importance of early detection of cancer. Nature of the disease; Malignant tumors being cancerous; Breast cancer as the most common cancer found in women; Suggestion that one should get the recommended screening so that if he develops cancer, he can get it treated early and...

  • Simpler testing for cancer looms.  // Executive Health's Good Health Report;May94, Vol. 30 Issue 8, p8 

    Reports on the ability of two tests to detect the presence of malignant cancers and to monitor the effects of treatment. Presence of a protein in the urine as an indicator of cancer; Indicators for the blood test; Information gleaned from the `Journal of the National Cancer Institute'.

  • Which fecal occult blood test is more reliable? Cerrato, Paul L. // RN;Jun93, Vol. 56 Issue 6, p20 

    Suggests that Hemoccult II is a better screen for colorectal cancer than HemoQuant, published in `Annual Internal Medicine'. Hemoccult as the more reliable screening tool for patients with malignancies anywhere from the juncture of the transverse and descending colon to the anus; Tests equally...

  • Cancer-Detection Guidelines.  // World Almanac & Book of Facts;2000, p732 

    No abstract available.

  • Subtle symptoms that signal danger. Lipman, Marvin M. // Consumer Reports on Health;Dec92, Vol. 4 Issue 12, p95 

    Lists some subtle symptoms that signal different types of cancer. Bowel changes; Rectal bleeding; Weight loss; Night sweats; Hoarseness; Leg pains; Red stretch marks; When to seek medical attention.

  • Lead exposure and cancer.  // Occupational Hazards;Apr96, Vol. 58 Issue 4, p29 

    Reports that a Finnish study has seemingly suggested that low-to-moderate occupational exposure to lead can increase the risk of nervous system cancer. Involvement of the Finnish Institute of Occupational Health; Results of study published in February 1996 issue of Journal of Occupational and...

  • Cancer screening rates are improving, but more progress is needed.  // Geriatrics;Jun96, Vol. 51 Issue 6, p60 

    Presents the abstract of the article `Trends in cancer screening--United States,' published in a 1996 issue of `Morbidity & Mortality Weekly Report.'

  • Cancer screening--how can we do better? Roylance, Rebecca; Waxman, Jonathan // BMJ: British Medical Journal (International Edition);07/04/98, Vol. 317 Issue 7150, p88 

    Opinion. Discusses cancer treatment and screening in Great Britain. Prevalence of cancer in Great Britain; Suggestion on how to limit errors in cancer screening; Information on technology for cancer screening.

  • Cancer-Detection Guidelines.  // World Almanac & Book of Facts;2001, p718 

    Presents guidelines and steps to diagnose a cancer or precursor as early as possible after it has developed. Guidelines for breast cancer, cervical cancer, colorectal cancer, endometrial cancer, oral cancer, prostate cancer, and skin cancer.

  • Cancer-Detection Guidelines.  // World Almanac & Book of Facts;2002, p743 

    Presents guidelines and steps to diagnose a cancer or precursor as early as possible after it has developed. Guidelines for breast cancer, cervical cancer, colorectal cancer, endometrial cancer, oral cancer, prostate cancer, and skin cancer.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics