Expression profiles of HA117 and its neighboring gene DPF3 in different colon segments of Hirschsprung's disease

Hang Liu; Yuanyuan Luo; Shuangshuang Li; Shiqi Wang; Ning Wang; Xianqing Jin
July 2014
International Journal of Clinical & Experimental Pathology;2014, Vol. 7 Issue 7, p3966
Academic Journal
No abstract available.


Related Articles

  • Study of the effect of miR-124 and the SOX9 target gene in Hirschsprung's disease. JIE MI; DONG CHEN; MEI WU; WEILIN WANG; HONG GAO // Molecular Medicine Reports;2014, Vol. 9 Issue 5, p1839 

    Hirschsprung's disease (HSCR) is a polygenic disease, of which the cause remains to be elucidated. It has been suggested that SRY-related HMG-box 9 (SOX9) is fundamental for the correct development of oligodendrocytes and astrocytes; however, not the development of neurons. There are currently...

  • Total colonic aganglionosis and Hirschsprung's disease: shades of the same or different? Moore, Sam W. // Pediatric Surgery International;Aug2009, Vol. 25 Issue 8, p659 

    Total colonic aganglionosis is a relatively uncommon form of Hirschsprung's disease (HSCR) occurring in approximately 2-13% of cases. It can probably be divided into total colonic aganglionosis (TCA; defined as aganglionosis extending from the anus to at least the ileocaecal valve, but no more...

  • Interstitial cells of Cajal are normally distributed in both ganglionated and aganglionic bowel in Hirschsprung’s disease. Newman, C. J.; Laurini, R. N.; Lesbros, Y.; Reinberg, O.; Meyrat, B. J. // Pediatric Surgery International;Nov2003, Vol. 19 Issue 9/10, p662 

    Surgery for Hirschsprung’s disease is often complicated by post-operative bowel motility disorders. The impact of intestinal neural histology on the surgical outcome has been previously studied, but no information is available concerning the influence of the distribution of interstitial...

  • Segmental dilatation of colon associated with anorectal malformation. Mahajan, J. K.; Mohanan, A.; Rao, K. L. N. // Journal of Indian Association of Pediatric Surgeons;Jan-Mar2007, Vol. 12 Issue 1, p32 

    Children with segmental dilatation of the colon suffer severe constipation and are clinically indistinguishable from Hirschsprung disease. Segmental dilatation of colon is rare in neonates. In this report, a neonate with unusual combination of segmental dilatation of the colon and high anorectal...

  • The Down-Regulation of Neuroligin-2 and the Correlative Clinical Significance of Serum GABA Over-Expression in Hirschsprung's Disease. Yang, Hongchao; Niu, Jianyi; Wang, Jian; Zhang, Fan; Zhang, Qiangye; Zhang, Wentong; Li, Aiwu // Neurochemical Research;Aug2014, Vol. 39 Issue 8, p1451 

    The goal of this study was to investigate the expression level of neuroligin-2 in different colon tissue segments of children with Hirschsprung's disease (HSCR) and the correlative clinical significance of serum Gamma-Aminobutyric Acid (serum GABA) in HSCR. Neuroligin-2 was assessed by...

  • Loss-of-function mutations in SIP1 Smad interacting protein 1 result in a syndromic Hirschsprung disease. Cacheux, Valère // Human Molecular Genetics;Jul2001, Vol. 10 Issue 14 

    Analyzes the mutations in SIP1 gene in a syndromic Hirschsprung disease. Determination of the chromosome 2 translocation breakpoint with the gene; Genomic structure and expression of the SIP1 gene; Alteration of the gene by heterozygous frameshift mutations; SIP1 expression pattern in different...

  • Expression and Significance of Neuroligins in Myenteric Cells of Cajal in Hirschsprung's Disease. Wang, Jian; Mou, Yaru; Zhang, Qiangye; Zhang, Fan; Yang, Hongchao; Zhang, Wentong; Li, Aiwu // PLoS ONE;Jun2013, Vol. 8 Issue 6, p1 

    Purpose: The aim of this study was to investigate the expression and significance of neuroligins in myenteric cells of Cajal (ICC-MY) in Hirschsprung’s disease (HSCR). Methods: Longitudinal muscle with adherent myenteric plexus (LMMP) from surgical excision waste colon of HSCR children...

  • Contribution of RET, NTRK3 and EDN3 to the expression of Hirschsprung disease in a multiplex family.  // Journal of Medical Genetics;Dec2009, Vol. 46 Issue 12, p10 

    Background: Hirschsprung disease (HSCR) is a developmental disorder caused by a defect in the neural crest neuroblast migration process. It is considered to be a paradigm of complex disorders, with many loci contributing to manifestation of the disease. Although HSCR commonly appears as a...

  • The Expression of Enteric Nerve Markers and Nerve Innervation in Total Colonic Aganglionosis. Yanlei Huang; Anupama, Basnet; Shan Zheng; Xianmin Xiao; Lian Chen // International Journal of Surgical Pathology;Jun2011, Vol. 19 Issue 3, p303 

    Objective. To study differences in the expression of various nerve markers between total colonic aganglionosis (TCA) and common-segment-type Hirschsprung’s disease (HD) using immunohistochemistry. Methods. All-layer colon and ileum specimens were extracted from 18 patients diagnosed with...

  • The distal level of normally innervated bowel in long segment colonic Hirschsprung's disease. Das, Kanishka; Kini, Usha; Babu, M. M.; Mohanty, Suravi; D'Cruz, Ashley J.; Babu, M K // Pediatric Surgery International;Jun2010, Vol. 26 Issue 6, p593 

    Purpose: The definitive surgical management of Hirschsprung's disease (HD) depends on an unambiguous histological diagnosis of bowel aganglionosis, as well as an accurate assessment of its proximal extent from the rectum or 'leveling'. This study aimed to evaluate and compare the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics